Results 161 to 170 of about 7,481 (302)
Model Choice Matters for Age Inference on the Red Giant Branch
The Astrophysical JournalGalactic archaeology relies on accurate stellar parameters to reconstruct the Galaxy's history, including information on stellar ages. While the precision of data has improved significantly in recent years, stellar models used for age inference have not ...
Leslie M. Morales +2 more
doaj +1 more source
FFNN–TabNet: An Enhanced Stellar Age Determination Method Based on TabNet
Applied SciencesThe precise ascertainment of stellar ages is pivotal for astrophysical research into stellar characteristics and galactic dynamics. To address the prevalent challenges of suboptimal accuracy in stellar age determination and limited proficiency in ...
Han Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
White dwarfs and the ages of stellar populations
, 2012 textOur group has developed a Bayesian modeling technique to determine the ages of stellar populations (in particular, open and globular clusters) using white dwarf (WD) cooling physics.
De Gennaro, Steven Andrew
core
The Astrophysical JournalWithin the molecular clouds of the Camelopardis OB1 (Cam OB1) association exists a region previously noted as one subgroup. However, bulk clustering from Gaia astrometry has recently shown three distinctive kinematically coherent groups, all found in a ...
Joseph Mullen +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
[C/N] Ages and Extra Mixing for [Fe/H] < −0.5: Insights from the LMC and SMC
The Astrophysical JournalThe [C/N]–age relation has become a powerful tool for reconstructing the formation history of the Milky Way (MW), providing the largest age sample for field giant stars.
Yuxi(Lucy) Lu +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
How precisely can we measure the ages of subgiant and giant stars?
The Open Journal of AstrophysicsPrecise stellar ages are fundamental to Galactic archaeology. However, obtaining reliable age estimates and uncertainties for field stars has been a long-standing challenge.
Cheyanne Shariat +2 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source