Results 191 to 200 of about 41,072 (339)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Clustering And 10 Myr Old Stellar Aggregates In The Orion Ob1 Association

open access: green, 2017
César Briceño   +2 more
openalex   +2 more sources

Volans-Carina: A New 90 Myr Old Stellar Association at 85 pc [PDF]

open access: bronze, 2018
Jonathan Gagné   +2 more
openalex   +1 more source

The Origins & Reservoirs of Exocomets. [PDF]

open access: yesSpace Sci Rev
Bannister M   +13 more
europepmc   +1 more source

Jupiter-like planets might be common in a low-density environment. [PDF]

open access: yesNat Commun, 2023
Gratton R   +8 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

New Low-mass Stars in the 25 Orionis Stellar Group and Orion OB1a Sub-association from SDSS-III/BOSS Spectroscopy [PDF]

open access: bronze, 2017
Genaro Suárez   +8 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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