Results 161 to 170 of about 2,699,264 (331)
, 2012 Thesis (B.S.)--University of Rochester. Dept. of Physics and Astronomy, 2003.I present here the classification of faint, close companions to several know young stellar objects (YSOs).
Forrest, William John (1945 - ) +2 more
core
Towards a Multi-Dimensional Stellar Classification System
Open Astronomy, 1997 Stock J. +4 more
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The presence of a planetary companion around its host star has been repeatedly linked with stellar properties, affecting the likelihood of substellar object formation and stability in the protoplanetary disc, thus presenting a key challenge in exoplanet ...
Zammit, Miguel A +3 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
A Review of Automated Stellar Spectral Classification and Surveys
, 1999 Modern spectroscopic surveys and automated classifiers are becoming so inextricably linked that it is difficult even to summarize one without discussing the other.
Bailer-Jones, Coryn A.L. +1 more
core
The Magellanic Clouds (MCs) are excellent locations to study stellar dust emission and its contribution to galaxy evolution. Through spectral and photometric classification, MCs can serve as a unique environment for studying stellar evolution and ...
Ghaziasgar, Sepideh +6 more
core +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source