Results 141 to 150 of about 2,699,264 (331)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Stellar physics with the ALHAMBRA photometric system

, 2012
GREAT-ESF Workshop: Stellar Atmospheres in the Gaia Era 23–24 June 2011, Vrije Universiteit Brussels, Belgium.The ALHAMBRA photometric system was specifically designed to perform a tomography of the Universe in some selected areas.
Olmo, Ascensión del, Cepa, Jordi, Cabrera-Caño, Jesús, Martínez, Vicente J., Castander, Francisco J., Márquez, Isabel, González Delgado, Rosa M., Infante, Leopoldo, Aguerri, J.A.L., Fernández-Soto, Alberto, Benítez, Narciso, Perea, Jaime, Prada, Francisco, Cristóbal-Hornillos, David, Aparicio Villegas, Teresa, Quintana, José María, Masegosa, Josefa, Cerviño, Miguel, Sánchez, Sebastián F., Broadhurst, Tom, Moles, Mariano, Alfaro, Emilio J.   +21 more
core   +1 more source

Analysis of Habitability and Stellar Habitable Zones from Observed Exoplanets

Galaxies
The investigation of exoplanetary habitability is integral to advancing our knowledge of extraterrestrial life potential and detailing the environmental conditions of distant worlds. In this analysis, we explore the properties of exoplanets situated with
Jonathan H. Jiang, Philip E. Rosen, Christina X. Liu, Qianzhuang Wen, Yanbei Chen   +4 more
doaj   +1 more source

45. Stellar Classification (Classification Stellaire) [PDF]

Transactions of the International Astronomical Union, 1994
D.J. MacConnel, R.O. Gray, C.B. Stephenson, M.J. Kurtz, J. Rountree, M. Grenon, D. Egret   +6 more
openaire   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Commission 45: stellar classification

, 2007
This report, like its predecessors, focuses on areas which have been especially active since the last General Assembly. Two major developments have been the unification of the T-dwarf standards and the new general catalogue of stellar spectral ...
Luri, Xavier, Pasinetti, Laura, Corbally, Christopher, Evans, Tom Lloyd, Straizys, Vytautas, Weiss, Werner, Giridhar, Sunetra, Bailer-Jones, Coryn, Kirkpatrick, Davy, Humphreys, Roberta, Minniti, Dante   +10 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

(Teff,log g,[Fe/H]) Classification of Low-Resolution Stellar Spectra using Artificial Neural Networks

, 1999
New generation large-aperture telescopes, multi-object spectrographs, and large format detectors are making it possible to acquire very large samples of stellar spectra rapidly.
Lambert, David L., Hippel, Ted von, Sneden, Christopher, Rossi, Silvia, Qu, Yuan, Prieto, Carlos Allende, Beers, Timothy C., Snider, Shawn   +7 more
core  

Red Stellar Populations and Dust Extinction toward W3

The Astrophysical Journal
We explore red stellar populations toward the W3 giant molecular cloud through the use of optical-to-infrared (IR) photometry and Gaia DR 3 data, simultaneously characterizing stellar content and properties of dust in the molecular medium.
J. L. Campbell, P. G. Martin, S. Song, M. Rahman, L. Einstein   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source