Results 81 to 90 of about 2,699,264 (331)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evolved Massive Stars at Low Metallicity. VII. The Lower Mass Limit of the Red Supergiant Population in the Large Magellanic Cloud

The Astrophysical Journal
The precise definition of the lower mass limit of red supergiant stars (RSGs) is an open question in astrophysics and does not attract much attention.
Ming Yang, Bo Zhang, Biwei Jiang, Jian Gao, Yi Ren, Shu Wang, Man I Lam, Hao Tian, Changqing Luo, Bingqiu Chen, Jing Wen   +10 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

starkiller: Subtracting Stars and Other Sources from IFU Spectroscopic Data Through Forward Modeling

The Astronomical Journal
We present starkiller , an open-source Python package for forward-modeling flux retrieval from integral field unit (IFU) spectrograph data cubes. starkiller simultaneously provides stellar spectral classification, relative velocity, and line-of-sight ...
Ryan Ridden-Harper, Michele T. Bannister, Sophie E. Deam, Thomas Nordlander   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Architectures of Planetary Systems. II. Trends with Host Star Mass and Metallicity

The Astronomical Journal
The current census of planetary systems displays a wide range of architectures. Extending earlier work, this paper investigates the correlation between our classification framework for these architectures and host stellar properties.
Alex R. Howe, Juliette C. Becker, Fred C. Adams   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Classification of Stars from Redshifted Stellar Spectra utilizing Machine Learning

, 2019
The classification of stellar spectra is a fundamental task in stellar astrophysics. There have been many explorations into the automated classification of stellar spectra but few that involve the Sloan Digital Sky Survey (SDSS). Stellar spectra from the
Brice, Michael J.
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