Results 81 to 90 of about 1,941,056 (293)

Architectures of Planetary Systems. II. Trends with Host Star Mass and Metallicity

open access: yesThe Astronomical Journal
The current census of planetary systems displays a wide range of architectures. Extending earlier work, this paper investigates the correlation between our classification framework for these architectures and host stellar properties.
Alex R. Howe   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Stellar Spectra Classification and Feature evaluation Based on Random Forest [PDF]

open access: yes, 2019
With the availability of multi-object spectrometers and the designing \& running of some large scale sky surveys, we are obtaining massive spectra. Therefore, it becomes more and more important to deal with the massive spectral data efficiently and ...
Li, Xiangru, Qiu, Kaibin, Lin, Yangtao
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

New morpho-kinematic classification: The two-dimensional spatial distribution of stellar specific angular momentum in late-type galaxies

open access: yesAstronomy & Astrophysics
Aims. The two-dimensional spatial distribution of stellar specific angular momentum (sAM) within galaxies has never been analysed. We seek to identify the morpho-kinematics of this property and its correlation with the total stellar sAM (j★) and the ...
Pacheco-Arias Juan Manuel   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

SPLASH: A Rapid Host-based Supernova Classifier for Wide-field Time-domain Surveys

open access: yesThe Astrophysical Journal Supplement Series
The upcoming Legacy Survey of Space and Time conducted by the Vera C. Rubin Observatory will detect millions of supernovae (SNe) and generate millions of nightly alerts, far outpacing available spectroscopic resources.
Adam Boesky   +4 more
doaj   +1 more source

Classification of Stellar Spectra with LLE

open access: yes, 2011
15 pages, 13 figures; accepted for publication in The Astronomical ...
Daniel, Scott F.   +4 more
openaire   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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