Results 151 to 160 of about 3,320,308 (251)

General Dynamics News

, 1968
Biweekly newsletter published for employees of the General Dynamics Fort Worth Division containing work-related information, updates about employees, and other ...
General Dynamics Corporation. Convair Division.
core  

Finite-Capacity Thermodynamics of Causal Horizons. [PDF]

Entropy (Basel)
Antiba CA.
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

General Dynamics Corporation Report GA-471

, 1958
From foreword: The TRIGA is a novel and unusually safe training, research, and isotope-production reactor that contains solid homogeneous uranium-zirconium-hydride-moderator fuel elements and operates at power levels in the range of from 10 kw to 250 ...
General Dynamics Corporation. General Atomic Division
core  

Astronomical spectra as language: Order-agnostic foundation model for low-SNR reconstruction and stellar parameter prediction. [PDF]

iScience
Xu J, Song X, Li Y, Wang C, Fu Z, Luo A, Liu J.   +6 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Stellar feedback drives the baryon deficiency in low-mass galaxies. [PDF]

Sci Adv
Yu H, Wang E, Chen Z, Péroux C, Zou H, He Z, Wang H, Lyu C, Jia C, Ma C, Kong X.   +10 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Simulation of Dense Star Map in Deep Space Based on Gaia Catalogue. [PDF]

Sensors (Basel)
Li P, Bao G, Zhou Z, Gong J.
europepmc   +1 more source