Results 171 to 180 of about 4,688 (310)

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Fundamentals of Interior Modelling and Challenges in the Interpretation of Observed Rocky Exoplanets. [PDF]

Space Sci Rev
Baumeister P, Miozzi F, Guimond CM, Steinmeyer ML, Dorn C, Karato SI, Bolmont É, Revol A, Thamm A, Noack L.   +9 more
europepmc   +1 more source

Stellar collapse dynamics with neutrino flavor changing neutral currents [PDF]

, 2007
Philip S. Amanik, George M. Fuller
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Expanding Targeted Instrumentation for Discovery Applications: Complement Reporter Ion Quantification with a Quadrupole-Ion Trap Instrument. [PDF]

J Proteome Res
Cruz ER, Johnson ANT, Pujari V, Zhang Q, Nguyen T, Stadlmeier M, Wang J, Jacob CC, McAlister GC, Remes PM, Wühr M.   +10 more
europepmc   +1 more source

Chemo-dynamics of the stellar component of the Sculptor dwarf galaxy II: dynamical properties and dark matter halo density [PDF]

José María Arroyo Polonio, R. Pascale, G. Battaglia, Guillaume F. Thomas, Carlo Nipoti, Eugene Vasiliev, Eline Tolstoy   +6 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

One-third of Sun-like stars are born with misaligned planet-forming disks. [PDF]

Nature
Biddle LI, Bowler BP, Morgan M, Tran QH, Wu YL.   +4 more
europepmc   +1 more source

Comments on the structure and dynamics of magnetic fields in stellar convection zones [PDF]

, 2005
M. Schuessler
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source