Results 131 to 140 of about 2,843,859 (384)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

New PARSEC evolutionary tracks of massive stars at low metallicity: testing canonical stellar evolution in nearby star-forming dwarf galaxies [PDF]

open access: yes, 2014
We extend the {\sl\,PARSEC} library of stellar evolutionary tracks by computing new models of massive stars, from 14\Msun to 350\Msun. The input physics is the same used in the {\sl\,PARSEC}~V1.1 version, but for the mass-loss rate which is included by ...
Jing Tang   +6 more
semanticscholar   +1 more source

Lithium abundance evolution in open clusters: Hyades, NGC752, and M67

open access: yes, 2013
Mixing mechanisms bring the Li from the base of the convective zone to deeper and warmer layers where it is destroyed. These mechanisms are investigated by comparing observations of Li abundances in stellar atmospheres to models of stellar evolution ...
Castro, Matthieu   +2 more
core   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Mixed modes in red giants: a window on stellar evolution [PDF]

open access: yes, 2014
Context. The detection of oscillations with a mixed character in subgiants and red giants allows us to probe the physical conditions in their cores. Aims. With these mixed modes, we aim at determining seismic markers of stellar evolution. Methods. Kepler
B. Mosser   +20 more
semanticscholar   +1 more source

Combining Stellar Evolution and Stellar Dynamics [PDF]

open access: yesSymposium - International Astronomical Union, 1996
There seem to me to be four approaches to the problem of computing the evolution of star clusters. Firstly, one might assume that our knowledge of the evolution of stars can be condensed into a subroutine that can be added to an N-body code. This subroutine would mainly have to give the radius and the time-dependent mass of a star as a function of its ...
openaire   +2 more sources

Effects of Magnetic Braking and Tidal Friction on Hot Jupiters

open access: yes, 2009
Tidal friction is thought to be important in determining the long-term spin-orbit evolution of short-period extrasolar planetary systems. Using a simple model of the orbit-averaged effects of tidal friction Eggleton, Kiseleva & Hut (1998), we analyse the
Adrian J. Barker   +7 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

StAGE: Stellar Archaeology-driven Galaxy Evolution

open access: yesThe Astrophysical Journal
We build a semiempirical framework of galaxy evolution (dubbed StAGE ) firmly grounded on stellar archaeology. The latter provides data-driven prescriptions that, on a population statistical ground, allow us to define the age and the star formation ...
Michele Bosi   +12 more
doaj   +1 more source

Modelling transport processes in stellar radiative interiors

open access: yesEPJ Web of Conferences, 2015
I report here on the different transport processes redistributing angular momentum and nuclides in stellar radiative interiors and on their modelling in stellar evolution codes.
Palacios A.
doaj   +1 more source

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