Results 131 to 140 of about 220,453 (316)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Dynamical Evolution of Globular Clusters with Stellar Mass Loss [PDF]

open access: yesJournal of Astronomy and Space Sciences, 1991
The dynamical evolution of globular clusters is studied using the orbit-averaged multicomponent Fokker-Planck equation. The original code developed by Cohn(1980) is modified to include the effect of stellar evolutions.
Chang-Hwan Kim   +2 more
doaj  

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

An Expanded Set of Los Alamos OPLIB Tables in MESA: Type-1 Rosseland-mean Opacities and Solar Models

open access: yesThe Astrophysical Journal
We present a set of 1194 Type-1 Rosseland-mean opacity tables for four different metallicity mixtures. These new Los Alamos OPLIB atomic radiative opacity tables are an order of magnitude larger in number than any previous opacity table release, and span
Ebraheem Farag   +13 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

TESS Subgiant and Lower-red-giant Asteroseismology in the Continuous Viewing Zones

open access: yesThe Astrophysical Journal
Asteroseismology, the study of stellar oscillations, and stellar modeling both offer profound insights into the fundamental properties and evolution of stars.
Sophia Grusnis   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Size–Mass Relation at Rest-frame 1.5 μm from JWST/NIRCam in the COSMOS-WEB and PRIMER-COSMOS Fields

open access: yesThe Astrophysical Journal
We present the galaxy stellar mass–size relation in the rest-frame near-IR (1.5 μ m) and its evolution with redshift up to z = 2.5. Sérsic profiles are measured for ∼26,000 galaxies with stellar masses M _⋆ > 10 ^9 M _⊙ from JWST/NIRCam F277W and F444W ...
Marco Martorano   +6 more
doaj   +1 more source

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