Results 291 to 300 of about 3,026,820 (400)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

High-temperature ²⁰⁵Tl decay clarifies ²⁰⁵Pb dating in early Solar System. [PDF]

Nature
Leckenby G, Sidhu RS, Chen RJ, Mancino R, Szányi B, Bai M, Battino U, Blaum K, Brandau C, Cristallo S, Dickel T, Dillmann I, Dmytriiev D, Faestermann T, Forstner O, Franczak B, Geissel H, Gernhäuser R, Glorius J, Griffin C, Gumberidze A, Haettner E, Hillenbrand PM, Karakas A, Kaur T, Korten W, Kozhuharov C, Kuzminchuk N, Langanke K, Litvinov S, Litvinov YA, Lugaro M, Martínez-Pinedo G, Menz E, Meyer B, Morgenroth T, Neff T, Nociforo C, Petridis N, Pignatari M, Popp U, Purushothaman S, Reifarth R, Sanjari S, Scheidenberger C, Spillmann U, Steck M, Stöhlker T, Tanaka YK, Trassinelli M, Trotsenko S, Varga L, Vescovi D, Wang M, Weick H, Yagüe Lopéz A, Yamaguchi T, Zhang Y, Zhao J.   +58 more
europepmc   +1 more source

The imprint of massive stellar evolution on circumstellar gas [PDF]

, 1995
Guillermo Garcı́a-Segura, Mordecai‐Mark Mac Low, N. Langer   +2 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Characterizing the luminosity components of luminous infrared galaxies in multi-wavelength from the X-ray to the far-infrared. [PDF]

Sci Rep
Ali AAM, Gadallah KAK, Shalabiea OM, Beheary MM.   +3 more
europepmc   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Enhanced production of ⁶⁰Fe in massive stars. [PDF]

Nat Commun
Spyrou A, Richman D, Couture A, Fields CE, Liddick SN, Childers K, Crider BP, DeYoung PA, Dombos AC, Gastis P, Guttormsen M, Hermansen K, Larsen AC, Lewis R, Lyons S, Midtbø JE, Mosby S, Muecher D, Naqvi F, Palmisano-Kyle A, Perdikakis G, Prokop C, Schatz H, Smith MK, Sumithrarachchi C, Sweet A.   +25 more
europepmc   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

A luminous and young galaxy at z = 12.33 revealed by a JWST/MIRI detection of Hα and [O iii]. [PDF]

Nat Astron
Zavala JA, Castellano M, Akins HB, Bakx TJLC, Burgarella D, Casey CM, Chávez Ortiz ÓA, Dickinson M, Finkelstein SL, Mitsuhashi I, Nakajima K, Pérez-González PG, Arrabal Haro P, Bergamini P, Buat V, Backhaus B, Calabrò A, Cleri NJ, Fernández-Arenas D, Fontana A, Franco M, Grillo C, Giavalisco M, Grogin NA, Hathi N, Hirschmann M, Ikeda R, Jung I, Kartaltepe JS, Koekemoer AM, Larson RL, McKinney J, Papovich C, Rosati P, Saito T, Santini P, Terlevich R, Terlevich E, Treu T, Yung LYA.   +39 more
europepmc   +1 more source

Analytical models for the structure and evolution of spherical stellar systems

, 1977
E. Davoust
openalex   +1 more source