Results 51 to 60 of about 219,464 (277)

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Stellar Pulsation and Evolution: A Combined Theoretical Renewal and Updated Models (SPECTRUM). I. Updating Radiative Opacities for Pulsation Models of Classical Cepheid and RR-Lyrae

open access: yesThe Astrophysical Journal
Pulsating stars are universally recognized as precise distance indicators and tracers of stellar populations. Their variability, combined with well-defined relationships between pulsation properties and intrinsic evolutionary parameters such as ...
Giulia De Somma   +3 more
doaj   +1 more source

The ups and downs of inferred cosmological lithium [PDF]

open access: yesEPJ Web of Conferences
I summarize the stellar side of the cosmological lithium problem(s). Evidence from independent studies is accumulating and indicates that stars may very well be fully responsible for lowering their surface lithium from the predicted primordial value to ...
Korn Andreas
doaj   +1 more source

Red supergiants and stellar evolution

open access: yes, 2013
We review the significant role played by red supergiants (RSGs) in stellar populations, and some challenges and questions they raise for theoretical stellar evolution. We present how metallicity and rotation modify the way stars go to the red part of the
Ekström, Sylvia   +4 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

TESS Asteroseismology of β Hydri: A Subgiant with a Born-again Dynamo

open access: yesThe Astrophysical Journal
The solar-type subgiant β Hyi has long been studied as an old analog of the Sun. Although the rotation period has never been measured directly, it was estimated to be near 27 days.
Travis S. Metcalfe   +14 more
doaj   +1 more source

Panchromatic fits to the Globular Cluster NGC 6366 [PDF]

open access: yes, 2013
We present panchromatic isochrone fits to the color magnitude data of the globular cluster NGC 6366, based on HST ACS/WFC and SOAR photometric data. Before performing the isochrone fits, we corrected the photometric data for differential reddening and ...
Bonatto, C.   +2 more
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

What Physical Factors Influence the Transformation between Blue Supergiants and Red Supergiants?

open access: yesThe Astrophysical Journal
The post-main-sequence evolution of massive stars is highly sensitive to key stellar model parameters, particularly initial rotational velocity and metallicity.
Yun He   +8 more
doaj   +1 more source

The Correlations of Stellar Tidal Disruption Rates with Properties of Massive Black Holes and Their Host Galaxies

open access: yesThe Astrophysical Journal, 2023
Stars can be either disrupted as tidal disruption events (TDEs) or swallowed whole by massive black holes (MBHs) at galactic centers when they approach sufficiently close to these MBHs.
Yunfeng Chen, Qingjuan Yu, Youjun Lu
doaj   +1 more source

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