Results 71 to 80 of about 220,693 (280)

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

The ups and downs of inferred cosmological lithium [PDF]

EPJ Web of Conferences
I summarize the stellar side of the cosmological lithium problem(s). Evidence from independent studies is accumulating and indicates that stars may very well be fully responsible for lowering their surface lithium from the predicted primordial value to ...
Korn Andreas
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

StAGE: Stellar Archaeology-driven Galaxy Evolution

The Astrophysical Journal
We build a semiempirical framework of galaxy evolution (dubbed StAGE ) firmly grounded on stellar archaeology. The latter provides data-driven prescriptions that, on a population statistical ground, allow us to define the age and the star formation ...
Michele Bosi, Andrea Lapi, Lumen Boco, Carlos A. Alvarez, Marcos M. Cueli, Giovanni Antinozzi, Meriem Behiri, Marika Giulietti, Marcella Massardi, Mario Spera, Alessandro Bressan, Carlo Baccigalupi, Luigi Danese   +12 more
doaj   +1 more source

Stellar Evolution and Convection in 3D Hydrodynamic Simulations of a Complete Burning Phase

Galaxies
Our understanding of stellar evolution and nucleosynthesis is limited by the uncertainties coming from the complex multi-dimensional processes in stellar interiors, such as convection and nuclear burning. Three-dimensional stellar models can improve this
Federico Rizzuti, Raphael Hirschi, Vishnu Varma, William David Arnett, Cyril Georgy, Casey Meakin, Miroslav Mocák, Alexander StJ. Murphy, Thomas Rauscher   +8 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Correlations between Ca ii H and K Emission and the Gaia M Dwarf Gap

The Astrophysical Journal
The Gaia M dwarf gap, also known as the Jao Gap, is a novel feature discovered in the Gaia Data Release 2 G versus BP-RP color–magnitude diagram. This gap represents a 17% decrease in stellar density in a thin magnitude band around the convective ...
Emily M. Boudreaux, Aylin Garcia Soto, Brian C. Chaboyer   +2 more
doaj   +1 more source