Results 91 to 100 of about 220,693 (280)

Boron Abundances in Early B Dwarfs of the Galactic Open Cluster NGC 3293

The Astrophysical Journal
New boron abundances or upper limits have been determined for eight early B stars in the young Galactic open cluster NGC 3293, using UV spectra obtained by the Hubble Space Telescope Cosmic Origins Spectrograph.
Charles R. Proffitt, Harim Jin, Simone Daflon, Daniel J. Lennon, Norbert Langer, Katia Cunha, Talawanda Monroe   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Tracing the History of Obscured Star Formation with the SIMBA Cosmological Galaxy Evolution Simulation

The Astrophysical Journal
We explore the cosmic evolution of the fraction of dust-obscured star formation predicted by the simba cosmological hydrodynamic simulations featuring an on-the-fly model for dust formation, evolution, and destruction.
Dhruv T. Zimmerman, Desika Narayanan, Katherine E. Whitaker, Romeel Davé   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Starspot Area Coverage: Correlation with Age and Spectral Type in FGK and M Stars

The Astrophysical Journal Letters
Starspots, analogous to sunspots, are surface manifestations of stellar magnetic activity. Their study provides crucial insights into stellar dynamo processes and the evolution of magnetic phenomena.
Alexandre Araújo, Ciria Lima, Fabian Menezes, Adriana Valio   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Evolution of the Physical Properties of the Most Massive Galaxies in Clusters and Their Protohalos

The Astrophysical Journal
We investigated the evolution of the physical properties of the brightest galaxies in clusters and their protohalos from z = 4 to z = 0. Galaxy clusters and groups are identified using a halo-based group finder applied to the COSMOS2020 galaxy catalog ...
Qingyang Li, Xiaohu Yang, Antonios Katsianis, Paola Popesso, Ilaria Marini, Y. Sophia Dai, Chengze Liu, Yipeng Jing, Jia-Sheng Huang, Marcin Sawicki   +9 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modelling Time-dependent Convective Penetration in 1D Stellar Evolution

The Astrophysical Journal
One-dimensional stellar evolution calculations produce uncertain predictions for quantities like the age, core mass, core compactness, and nucleosynthetic yields; a key source of uncertainty is the modeling of interfaces between regions that are ...
Cole Johnston, Mathias Michielsen, Evan H. Anders, Mathieu Renzo, Matteo Cantiello, P. Marchant, Jared A. Goldberg, Richard H. D. Townsend, Gautham Sabhahit, Adam S. Jermyn   +9 more
doaj   +1 more source