Results 61 to 70 of about 214,013 (271)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Galaxy formation with cold gas accretion and evolving stellar initial mass function

, 2010
The evolution of the galaxy stellar mass function is especially useful to test the current model of galaxy formation. Observational data have revealed a few inconsistencies with predictions from the $\Lambda {\rm CDM}$ model.
Chen, Dongni, Kang, Xi, Lin, WeiPeng, Skibba, Ramin A.   +3 more
core   +1 more source

Combining Stellar Evolution and Stellar Dynamics [PDF]

Symposium - International Astronomical Union, 1996
There seem to me to be four approaches to the problem of computing the evolution of star clusters. Firstly, one might assume that our knowledge of the evolution of stars can be condensed into a subroutine that can be added to an N-body code. This subroutine would mainly have to give the radius and the time-dependent mass of a star as a function of its ...
openaire   +2 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

The Multiple Origin of Blue Straggler Stars: Theory vs. Observations

, 2014
In this chapter we review the various suggested channels for the formation and evolution of blue straggler stars (BSSs) in different environments and their observational predictions.
A. Hypki, A. Jorissen, A. M. Geller, A. M. Geller, A. M. Geller, A. S. Hamers, A. Tokovinin, B. W. Carney, B. W. Carney, C. Abate, D. Fabrycky, D. Raghavan, D. T. F. Weldrake, D. T. F. Weldrake, D. W. Latham, F. Antonini, F. R. Ferraro, F. R. Ferraro, H. B. Perets, H. B. Perets, H. B. Perets, H. B. Perets, J. G. Hills, J. M. Fregeau, J. M. Nemec, J. R. Hurley, L. G. Kiseleva, L. Lovisi, L. Lovisi, M. Auriere, M. B. Davies, M. L. Lidov, M. M. Shara, M. Mapelli, M. Mateo, N. Leigh, N. Leigh, P. Eggleton, P. J. T. Leonard, P. J. T. Leonard, P. J. T. Leonard, P. J. T. Leonard, P. J. T. Leonard, P. P. Eggleton, P. P. Eggleton, R. D. Mathieu, R. D. McClure, R. Kippenhahn, R. S. Harrington, S. Chatterjee, S. M. Rucinski, T. Dermine, T. Mazeh, W. Benz, W. H. McCrea, W. H. McCrea, W. I. Clarkson, W. Landsman, X. Chen, Y. Kozai   +59 more
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Reference grids of stellar models and oscillation frequencies: Data from the CESAM stellar evolution code and ADIPLS oscillation programme

, 2008
We present grids of stellar models and their associated oscillation frequencies that have been used by the CoRoT Seismology Working Group during the scientific preparation of the CoRoT mission.
Lebreton, Yveline, Michel, Eric
core   +2 more sources

Current Problems In Stellar Evolution

, 2018
The theory of stellar evolution plays a central role in astrophysics as stellar models are used to infer properties for Galactic and Extragalactic stellar populations as well as exoplanetary systems. However, despite decades of experience, stellar models still face major issues linked to transport processes of chemicals and angular momentum.
openaire   +4 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source