Results 51 to 60 of about 4,904 (241)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The impact of alpha/Fe enhanced stellar evolutionary tracks on the ages of elliptical galaxies [PDF]
, 2003 We complement our study of $\alpha/{\rm Fe}$ enhanced stellar population models of Lick absorption indices (Thomas et al. [CITE]) by comparing two sets of $\alpha/{\rm Fe}$ enhanced models. In both models the impact on Lick indices due to $\alpha/{\rm Fe}
D. Thomas +3 more
core +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Stellar Models (Evolutionary Tracks)
Stellar models parameterized by evolutionary tracks (evolution of a star over time)
Speagle, Josh
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Predicting Photospheric Ultraviolet Emission from Stellar Evolutionary Models
The Astrophysical JournalAbstract Stellar ultraviolet (UV) emission serves as a crucial indicator for estimating magnetic activity and evaluating the habitability of exoplanets orbiting stars. In this paper, we present a straightforward method to derive stellar photospheric UV emission for F to M main-sequence stars.
Song Wang +3 more
openaire +2 more sources
Detailed AGB evolutionary models and near-infrared colours of intermediate-age stellar populations: tests on star clusters [PDF]
Astronomy & Astrophysics, 2014 12 pages, 14 figures, accepted for publication in A& ...
Salaris, M. +4 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Pre–Main-Sequence Eclipsing Binary TY Coronae Australis: Precise Stellar Dimensions and Tests of Evolutionary Models [PDF]
The Astronomical Journal, 1998 We analyze new photometric data for the Herbig Be eclipsing binary TY CrA, which securely reveal the secondary eclipse, ~0.03 mag deep in y. From the light-curve solution and our previous spectroscopic data, absolute dimensions of the primary and secondary stars are derived.
Casey, B.W. +4 more
openaire +1 more source