Results 71 to 80 of about 1,638 (254)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Rapid Stellar and Binary Population Synthesis with COMPAS: Methods Paper II

The Astrophysical Journal Supplement Series
The COMPAS ( http://compas.science ) public rapid binary population synthesis code has undergone a number of key improvements since the original COMPAS methods paper was published.
Team COMPAS, Ilya Mandel, Jeff Riley, Adam Boesky, Adam Brček, Ryosuke Hirai, Veome Kapil, Mike Y. M. Lau, JD Merritt, Nicolás Rodríguez-Segovia, Isobel Romero-Shaw, Yuzhe Song, Simon Stevenson, Avi Vajpeyi, L. A. C. van Son, Alejandro Vigna-Gómez, Reinhold Willcox   +16 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Evolutionary stellar models for multiple population Globular Clusters: theoretical framework and interpretative analysis [PDF]

, 2012
6 pages, 2 figures. Invited contribution at the meeting "Reading the book of Globular Clusters with the lens of stellar evolution", 26 - 28 November 2012, Monte Porzio Catone ...
Cassisi, S, Salaris, M, Pietrinferni, A
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Stellar Library for Evolutionary Synthesis Modeling Including Variable AGB Stars

, 1999
4 pages, to appear in the PASP Conference Proceedings series of the Workshop "Spectrophotometric dating of stars and galaxies", Annapolis, Maryland (U.S.A.), eds. I. Hubeny, S.
Mouhcine, M., Lancon, A.
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Model Choice Matters for Age Inference on the Red Giant Branch

The Astrophysical Journal
Galactic archaeology relies on accurate stellar parameters to reconstruct the Galaxy's history, including information on stellar ages. While the precision of data has improved significantly in recent years, stellar models used for age inference have not ...
Leslie M. Morales, Jamie Tayar, Zachary R. Claytor   +2 more
doaj   +1 more source

FASTAR

Astronomy & Astrophysics
Standard evolutionary synthesis models rely on the assumption of a fully sampled stellar initial mass function (IMF). Under this assumption, the age, chemical composition, and IMF uniquely define the predicted absorption spectra.
Martín-Navarro Ignacio, Vazdekis Alexandre, Peralta de Arriba Luis, Alonso Asensio Isaac, Iglesias Navarro Patricia, Angeloudi Eirini, La Barbera Francesco, Cerviño Miguel, Fahrion Katja, Jerabkova Tereza, Beasley Michael A., Falcón-Barroso Jesús, Huertas-Company Marc, Sánchez Sebastián F., Jethwa Prashin   +14 more
doaj   +1 more source

EVOLUTIONARY MODELS OF ROTATING DENSE STELLAR SYSTEMS WITH EMBEDDED BLACK HOLES

Publications of The Korean Astronomical Society, 2015
We present evolutionary models of rotating self-gravitating systems (e.g. globular clusters, galaxy cores). These models are characterized by the presence of an initial axi-symmetry due to rotation. Central black hole seeds are included in our models, and black hole growth due to the consumption of stellar matter is simulated until the central ...
openaire   +2 more sources