Results 91 to 100 of about 69,893 (289)

The Formation of Blue Large-amplitude Pulsators from White-dwarf Main-sequence Star Mergers

The Astrophysical Journal, 2023
Blue large-amplitude pulsators (BLAPs) are hot low-mass stars that show large-amplitude light variations likely due to radial oscillations driven by iron group opacities. Period changes provide evidence of both secular contraction and expansion among the
Xianfei Zhang, C. Simon Jeffery, Jie Su, Shaolan Bi   +3 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Model Choice Matters for Age Inference on the Red Giant Branch

The Astrophysical Journal
Galactic archaeology relies on accurate stellar parameters to reconstruct the Galaxy's history, including information on stellar ages. While the precision of data has improved significantly in recent years, stellar models used for age inference have not ...
Leslie M. Morales, Jamie Tayar, Zachary R. Claytor   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Impact of Irradiation on the Radius and Thermal Evolution of Transiting Brown Dwarfs

The Astrophysical Journal
Masses and radii of transiting brown dwarfs can be measured directly, in contrast to isolated field brown dwarfs, whose mass and radius inferences are model dependent.
Sagnick Mukherjee, Jonathan J. Fortney, Theron W. Carmichael, C. Evan Davis, Daniel P. Thorngren   +4 more
doaj   +1 more source

Revealing infrared populations of nearby galaxies using the Spitzer Space Telescope

, 2009
Due to their brightness in infrared, asymptotic giant branch (AGB) stars are in important evolutionary stage to be understood at this wavelength. In particular, in next decades, when the infrared optimised telescopes, such as the JWST and the ELT are in ...
Cioni, Marigo, Matsuura, Mikako Matsuura, Wachter   +4 more
core   +1 more source

EVOLUTIONARY MODELS OF ROTATING DENSE STELLAR SYSTEMS WITH EMBEDDED BLACK HOLES

Publications of The Korean Astronomical Society, 2015
We present evolutionary models of rotating self-gravitating systems (e.g. globular clusters, galaxy cores). These models are characterized by the presence of an initial axi-symmetry due to rotation. Central black hole seeds are included in our models, and black hole growth due to the consumption of stellar matter is simulated until the central ...
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

On Convective Turnover Times and Dynamos in Low-mass Stars

The Astrophysical Journal
The relationship between magnetic activity and Rossby number is one way through which stellar dynamos can be understood. Using measured rotation rates and X-ray to bolometric luminosity ratios of an ensemble of stars, we derive empirical convective ...
Seth Gossage, Rocio Kiman, Kristina Monsch, Amber A. Medina, Jeremy J. Drake, Cecilia Garraffo, Yuxi(Lucy) Lu, Joshua D. Wing, Nicholas J. Wright   +8 more
doaj   +1 more source