Results 91 to 100 of about 7,730,975 (288)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
EVOLUTIONARY MODELS OF ROTATING DENSE STELLAR SYSTEMS WITH EMBEDDED BLACK HOLES
Publications of The Korean Astronomical Society, 2015 We present evolutionary models of rotating self-gravitating systems (e.g. globular clusters, galaxy cores). These models are characterized by the presence of an initial axi-symmetry due to rotation. Central black hole seeds are included in our models, and black hole growth due to the consumption of stellar matter is simulated until the central ...
openaire +2 more sources
A Stellar Library for Evolutionary Synthesis Modeling Including Variable AGB Stars
, 1999 4 pages, to appear in the PASP Conference Proceedings series of the Workshop "Spectrophotometric dating of stars and galaxies", Annapolis, Maryland (U.S.A.), eds. I. Hubeny, S.
Mouhcine, M., Lancon, A.
openaire +2 more sources
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Evolutionary stellar models for multiple population Globular Clusters: theoretical framework and interpretative analysis [PDF]
, 2012 6 pages, 2 figures. Invited contribution at the meeting "Reading the book of Globular Clusters with the lens of stellar evolution", 26 - 28 November 2012, Monte Porzio Catone ...
Cassisi, S, Salaris, M, Pietrinferni, A
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Evolutionary population synthesis and the Magellanic Clouds clusters
, 1986 Synthetic bolometric luminosities and U, B, V fluxes are computed for models of globular clusters using available stellar evolutionary tracks for two chemical compositions and for a large interval of age.
CAPUZZO DOLCETTA, Roberto Angelo
core
Model Choice Matters for Age Inference on the Red Giant Branch
The Astrophysical JournalGalactic archaeology relies on accurate stellar parameters to reconstruct the Galaxy's history, including information on stellar ages. While the precision of data has improved significantly in recent years, stellar models used for age inference have not ...
Leslie M. Morales +2 more
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source