Results 111 to 120 of about 7,730,975 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamical Masses for 23 Pre-main-sequence Stars in Upper Scorpius: A Critical Test of Stellar Evolutionary Models

The Astrophysical Journal
We present dynamical masses for 23 pre-main-sequence (PMS) K- and M-type stars in the Upper Scorpius star-forming region. These masses were derived from the Keplerian rotation of CO disk gas using the Markov Chain Monte Carlo radiative-transfer package ...
A. P. M. Towner, J. A. Eisner, P. D. Sheehan, L. A. Hillenbrand, Y.-L. Wu   +4 more
doaj   +1 more source

Stellar age determination using deep neural networks

Astronomy & Astrophysics
Context. Recent spectroscopic surveys provide element abundances for large samples of Milky Way stars, from which stellar parameters can be inferred.
Boin T., Casamiquela L., Haywood M., Di Matteo P., Lebreton Y., Uddin M., Reese D. R.   +6 more
doaj   +1 more source

Constraining angular momentum transport processes in stellar interiors with red-giant stars in the open cluster NGC6819

EPJ Web of Conferences, 2015
Clusters are excellent test benches for verification and improvement of stellar evolution theory. The recent detection of solar-like oscillations in G-K giants in the open cluster NGC6819 with Kepler provides us with independent constraints on the masses
Lagarde, N, Miglio, A., Eggenberger, P., Montalbán, J, Bossini, D   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Reference grids of stellar models and oscillation frequencies. Data from the CESAM stellar evolution code and ADIPLS oscillation programme

, 2008
International audienceWe present grids of stellar models and their associated oscillation frequencies that have been used by the CoRoT Seismology Working Group during the scientific preparation of the CoRoT mission.
Michel, Eric, Lebreton, Yveline
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effect of Matter Accretion on Lithium Enhancement of Giants

The Astrophysical Journal
A subset of low-mass giants (
Xue-Feng Li, Jian-Rong Shi, Yan Li, Hong-Liang Yan, Jing-Hua Zhang, Fei Guo   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

CHRONOS: Towards a self-consistent and absolute stellar age scale

Astronomy & Astrophysics
Context. Establishing a self-consistent age scale for stellar populations requires physically well-calibrated chronometers. Among these, lithium-based diagnostics, particularly the lithium depletion boundary (LDB), provide one of the most robust age ...
González-Ramírez L., Barrado D., Olivares J., Berihuete A., Sarro L. M., Palmero F. J.   +5 more
doaj   +1 more source