Results 121 to 130 of about 69,893 (289)

Stellar Evolution in Real Time. II. R Hydrae and an Open-Source Grid of >3000 Seismic TP-AGB Models Computed with MESA

open access: yesThe Astrophysical Journal
We present a comprehensive characterization of the evolved thermally pulsing asymptotic giant branch (TP-AGB) star R Hydrae (R Hya), building on the techniques applied in Stellar Evolution in Real Time I (Molnár et al.) to T Ursae Minoris.
Meridith Joyce   +5 more
doaj   +1 more source

The Power of Asteroseismology for Early Stellar Evolution

open access: yesFrontiers in Astronomy and Space Sciences, 2019
Stars are the building blocks of planetary systems, clusters, associations, and galaxies. The evolution of stars is driven by physical processes in their interiors making theory of stellar interior structure and evolution an important ingredient of ...
Konstanze Zwintz
doaj   +1 more source

On the evolutionary and pulsation mass of Classical Cepheids: III. the case of the eclipsing binary Cepheid CEP0227 in the Large Magellanic Cloud

open access: yes, 2012
We present a new Bayesian approach to constrain the intrinsic parameters (stellar mass, age) of the eclipsing binary system CEP0227 in the LMC.
Alcock   +59 more
core   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evidence that Mass Loss on the Red Giant Branch Decreases with Metallicity

open access: yesThe Astrophysical Journal
Mass loss on the red giant branch (RGB) influences stellar evolution, properties of stellar populations, and Galactic chemical enrichment, yet remains poorly constrained observationally. Current models provide limited insight into how stellar properties,
Yaguang Li
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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