Results 141 to 150 of about 69,893 (289)

A Classical Cepheid in a LMC eclipsing binary: evidence of shortcomings in current stellar evolutionary models?

, 2011
The recent discovery and analysis of a classical Cepheid in the well detached, double-lined, eclipsing binary OGLE-LMC-CEP0227, has provided the first determination of the dynamical mass of a classical Cepheid variable to an unprecedented 1% accuracy. We show here that modern stellar evolution models widely employed to study Galactic and extragalactic ...
Cassisi, Santi, Salaris, Maurizio
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

A Semi-analytical Model for Stellar Evolution in AGN Disks

The Astrophysical Journal
Disks of gas accreting onto supermassive black holes may host numerous stellar-mass objects, formed within the disk or captured from a nuclear star cluster.
Alexander J. Dittmann, Matteo Cantiello
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Dynamical Mass of the Ophiuchus Intermediate-mass Stellar System S1 with DYNAMO-VLBA

The Astronomical Journal
We report dynamical mass measurements of the individual stars in the most luminous and massive stellar member of the nearby Ophiuchus star-forming region, the young tight binary system S1.
Jazmín Ordóñez-Toro, Sergio A. Dzib, Laurent Loinard, Gisela Ortiz-León, Marina A. Kounkel, Josep M. Masqué, S.-N. X. Medina, Phillip A. B. Galli, Trent J. Dupuy, Luis F. Rodríguez, Luis H. Quiroga-Nuñez   +10 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Asymptotic Giant Branch Mass-loss Rates and Metal Yields from Scaled Mixing-length and Mass-loss Parameters

The Astrophysical Journal
Stars on the asymptotic giant branch (AGB) enrich the interstellar medium with carbon, nitrogen, and dust, which in turn boost cooling and promote future generations of planet and star formation.
Ezra Huscher, Kristian Finlator, Jason Jackiewicz   +2 more
doaj   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source