Results 151 to 160 of about 69,893 (289)
Characterization of the Host Binary of the Directly Imaged Exoplanet HD 143811 AB b
The Astrophysical Journal LettersHD 143811 AB is the host star to the directly imaged planet HD 143811 AB b, which was recently discovered using data from the Gemini Planet Imager and Keck NIRC2.
Anne E. Peck +52 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu +14 more
wiley +1 more source
Asteroseismically Inferred Ages of 132,000 Red Giants with TESS
The Astrophysical Journal Supplement SeriesNASA’s Transiting Exoplanet Survey Satellite mission has identified at least 158,000 oscillating red giants, increasing the known sample by roughly an order of magnitude.
Artemis Theano Theodoridis +2 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Bridging the Prandtl Number Gap: 3D Simulations of Thermohaline Convection in Astrophysical Regimes
The Astrophysical Journal LettersThermohaline convection (also known as fingering convection or thermohaline mixing) occurs in stellar radiation zones where a sufficient inversion of the mean molecular weight is present.
Adrian E. Fraser
doaj +1 more source
Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz +9 more
wiley +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Hidden Figures of Globular Clusters: Integrated Stellar Populations Impacted by Hot Subdwarfs
The Astrophysical JournalGlobular clusters (GCs) are fundamental for understanding the integrated light of old stellar populations and galaxy assembly processes. However, the role of hot, evolved stars, such as horizontal branch (HB), extreme HB, and blue stragglers, remains ...
Thayse A. Pacheco +10 more
doaj +1 more source