Results 31 to 40 of about 974 (262)
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks +5 more
wiley +1 more source
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille +9 more
wiley +1 more source
Structure and evolution of high-mass stellar mergers [PDF]
In young dense clusters repeated collisions between massive stars may lead to the formation of a very massive star (above 100 Msun). In the past the study of the long-term evolution of merger remnants has mostly focussed on collisions between low-mass stars (up to about 2 Msun) in the context of blue-straggler formation.
Glebbeek, E. +3 more
openaire +3 more sources
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar +7 more
wiley +1 more source
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
Extreme emission line galaxies (EELGs), where nebular emissions contribute 30%–40% of the flux in certain photometric bands, are ubiquitous in the early Universe ( z > 6).
Anshu Gupta +9 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Mergers of accreting stellar-mass black holes [PDF]
We present post-Newtonian $N$-body simulations on mergers of accreting stellar-mass black holes (BHs), where such general relativistic effects as the pericenter shift and gravitational wave (GW) emission are taken into consideration. The attention is concentrated on the effects of the dynamical friction and the Hoyle-Lyttleton mass accretion by ambient
Tagawa, Hiromichi +2 more
openaire +3 more sources
Massive quiescent galaxies at high redshift show significantly more compact morphology than their local counterparts. To examine their internal structure across a wide redshift range and investigate potential redshift dependence, we performed spatially ...
Novan Saputra Haryana +14 more
doaj +1 more source

