Results 141 to 150 of about 373 (258)

Direct detection of an asteroid's heliocentric deflection: The Didymos system after DART. [PDF]

Sci Adv
Makadia R, Chesley SR, Herald D, Farnocchia D, Chabot NL, Naidu SP, Rivkin AS, Siakas A, Souami D, Tanga P, Tsavdaridis S, Tsiganis K, Bouquillon S, Eggl S.   +13 more
europepmc   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Occultation constraints on solar system formation models. [PDF]

Philos Trans A Math Phys Eng Sci
Buie MW, Keller JM, Nesvorný D, Porter SB.   +3 more
europepmc   +1 more source

Spatial Transcriptomics Reveals a T Cell‐Mediated Microglial Activation Axis of Immune Checkpoint Inhibition‐Related Adverse Events in the Brain

Advanced Science, EarlyView.
Immune checkpoint inhibition (ICI) reshapes the hippocampal neuroimmune niche. Spatial transcriptomic profiling and human brain histological analyses identify neuroinflammation and altered neuronal and glial programs. Notably, T cell depletion prevents ICI‐driven microglial activation, establishing the T cell–microglia crosstalk axis as a driving ...
Devyani Swami, Sanad M. El‐Khatib, Suhas Sureshchandra, Elise Nguyen, Janaki Manoja Vinnakota, Robert Zeiser, Shivashankar Othy, Munjal M. Acharya   +7 more
wiley   +1 more source

Unveiling Anisotropic in‐Plane Thermal Conductivity and Thermal Expansion Coefficient in Low‐Symmetry Few‐Layer ReS2

Advanced Science, EarlyView.
Simultaneous two‐mode Raman thermometry reveals strong in‐plane anisotropic thermal conductivity and thermal expansion coefficients in low‐symmetry few‐layer ReS2. By decoupling thermal transport along the crystallographic a‐ and b‐axes within a single optical configuration, this study provides robust experimental evidence and ab initio theoretical ...
Manab Mandal, Prahalad Kanti Barman, Susmita Jana, Saroj Poudyal, Kaushalya Kumari, Sourav Mondal, Abhishek Misra, Birabar Ranjit Kumar Nanda, Pramoda Kumar Nayak, Kanikrishnan Sethupathi   +9 more
wiley   +1 more source

Geodetic Investigations of the Europa Clipper Mission. [PDF]

Space Sci Rev
Steinbrügge G, Park RS, Roberts JH, Bland M, Brooks S, Castillo-Rogez J, Cascioli G, Genova A, Greathouse T, Hussmann H, Kirk R, Magnanini A, Mazarico E, Nimmo F, Park MS, Petricca F, Retherford K, Schroeder DM, Soderlund KM, Tortora P, Zannoni M.   +20 more
europepmc   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

The hidden mysteries of our ice giant planets. [PDF]

Nat Commun
de Villa K, Ge H.
europepmc   +1 more source

Pronounced Suppression and X-Pattern Merging of Equatorial Ionization Anomalies After the 2022 Tonga Volcano Eruption. [PDF]

J Geophys Res Space Phys, 2022
Aa E, Zhang SR, Wang W, Erickson PJ, Qian L, Eastes R, Harding BJ, Immel TJ, Karan DK, Daniell RE, Coster AJ, Goncharenko LP, Vierinen J, Cai X, Spicher A.   +14 more
europepmc   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source