Results 41 to 50 of about 3,470 (308)
The Astrophysical Journal Supplement Series, 2023 We update the capabilities of the open-knowledge software instrument Modules for Experiments in Stellar Astrophysics ( MESA ). The new auto _ diff module implements automatic differentiation in MESA , an enabling capability that alleviates the need for ...
Adam S. Jermyn +21 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
On a physical theory of stellar spectra [PDF]
Proceedings of the Royal Society of London. Series A, Containing Papers of a Mathematical and Physical Character, 1921 The present paper embodies an attempt towards a physical explanation of the ordered gradation in the spectra of stars—a subject in which pioneering work was done by the late Sir Norman Lockyer, but which was worked up with systematic thoroughness at the Harvard College Observatory, under the lead of the late Prof. E. C. Pickering and Miss A. J. Cannon.
openaire +3 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Stellar Flare Statistics - Physical Consequences [PDF]
International Astronomical Union Colloquium, 1989 AbstractThe observational data permit us to establish clear statistical correlations between different parameters of stellar flare activity and the characteristics of quiet stars. These relations are: (i)between energies and frequencies of flares on stars of different luminosities;(ii)between total radiation energies of flares and quiet stars both in X-
openaire +3 more sources
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Solar-Like Oscillators in the Kepler Era: A Review
Frontiers in Astronomy and Space Sciences, 2021 Many late-type stars across the Milky Way exhibit observable pulsations similar to our Sun that open up a window into stellar interiors. The NASA Kepler mission, a space-based photometric telescope, measured the micro-magnitude luminosity fluctuations ...
Jason Jackiewicz
doaj +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
The Astrophysical Journal, 2023 Asteroseismology has been used extensively in recent years to study the interior structure and physical processes of main-sequence stars. We consider prospects for using pressure modes (p-modes) near the frequency of maximum oscillation power to probe ...
Christopher J. Lindsay +2 more
doaj +1 more source