Results 141 to 150 of about 12,166 (296)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

On the Origin of Fast-rotating Stars. I. Photometric Calibration and Results of AO-assisted BVRI+Hα Imaging of NGC 330 with SAMI/SOAR

The Astrophysical Journal
H α emission is a clear indicator of circumstellar activity in Be stars, historically employed to assess the classical Be star (CBe) population in young open clusters (YOCs).
Felipe Navarete, Pedro Ticiani dos Santos, Alex Cavaliéri Carciofi, André Luiz Figueiredo   +3 more
doaj   +1 more source

NORMAL AND OUTLYING POPULATIONS OF THE MILKY WAY STELLAR HALO AT [Fe/H] <–2 [PDF]

, 2013
Judith G. Cohen, N. Christlieb, I. Thompson, Andrew McWilliam, Stephen A. Shectman, D. Reimers, L. Wisotzki, Evan N. Kirby   +7 more
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Age of Massive Galaxies at Redshift 8

The Astrophysical Journal
Recent James Webb Space Telescope data analyses have shown that massive red galaxies existed at redshifts z ≳ 6, a discovery that is difficult to understand in the context of standard cosmology (ΛCDM).
M. López-Corredoira, F. Melia, J.-J. Wei, C.-Y. Gao   +3 more
doaj   +1 more source

The HST  large programme on ω Centauri – I. Multiple stellar populations at the bottom of the main sequence probed in NIR–Optical [PDF]

, 2017
A. P. Milone, A. F. Marino, L. R. Bedin, Jay Anderson, Dániel Apai, Andrea Bellini, P. Bergeron, Adam J. Burgasser, Aaron Dotter, Jon M. Rees   +9 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Hidden Figures of Globular Clusters: Integrated Stellar Populations Impacted by Hot Subdwarfs

The Astrophysical Journal
Globular clusters (GCs) are fundamental for understanding the integrated light of old stellar populations and galaxy assembly processes. However, the role of hot, evolved stars, such as horizontal branch (HB), extreme HB, and blue stragglers, remains ...
Thayse A. Pacheco, Paula R. T. Coelho, Lucimara P. Martins, Ricardo P. Schiavon, Erik V. R. de Lima, Marcos P. Diaz, Domenico Nardiello, Ronaldo S. Levenhagen, Rogério Riffel, Charles J. Bonatto, Ana L. Chies-Santos   +10 more
doaj   +1 more source

Spatially-resolved stellar populations of nearby galaxies in multi-filter surveys [PDF]

, 2016
I. San Roman, A. J. Cenarro, L. A. Díaz-García, C. López-Sanjuán, J. Varela, the J-PLUS Team   +5 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source