Results 151 to 160 of about 6,178,117 (397)

A Census of Star Formation Histories of Massive Galaxies at 0.6 < z < 1 from Spectrophotometric Modeling Using Bagpipes and Prospector

open access: yesThe Astrophysical Journal
We present individual star formation histories (SFHs) of ∼3000 massive galaxies (log( M _* / M _⊙ ) > 10.5) from the Large Early Galaxy Astrophysics Census spectroscopic survey at a lookback time of ∼7 billion yr and quantify the population trends ...
Yasha Kaushal   +15 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Stellar population and the origin of intra-cluster stars around brightest cluster galaxies: the case of NGC 3311

open access: yes, 2011
Context. We investigate the stellar population and the origin of diffuse light around brightest cluster galaxies. Aims. We study the stellar population of the dynamically hot stellar halo of NGC 3311, the brightest galaxy in the Hydra I cluster, and ...
Abadi   +54 more
core   +1 more source

A study of stellar population of intermediate-age globular cluster NGC 2249

open access: yesResults in Physics, 2020
The Large Magellanic Cloud (LMC) star cluster NGC 2249 has been found to exhibit an extended main-sequence turn-off (eMSTO) in the color-magnitude diagram (CMD) derived from the data of the Hubble Space Telescope (HST).
Zhongmu Li   +4 more
doaj  

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

The Origin of Young Stellar Populations in NGC 1783: Accretion of External Stars

open access: yesThe Astrophysical Journal
The presence of young stellar populations in the Large Magellanic Cloud cluster NGC 1783 has caught significant attention, with suggestions ranging from it being a genuine secondary stellar generation to a population of blue straggler stars or simply ...
Li Wang   +6 more
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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