Results 221 to 230 of about 108,892 (343)

Photometric detection at 7.7 μm of a galaxy beyond redshift 14 with JWST/MIRI. [PDF]

Nat Astron
Helton JM, Rieke GH, Alberts S, Wu Z, Eisenstein DJ, Hainline KN, Carniani S, Ji Z, Baker WM, Bhatawdekar R, Bunker AJ, Cargile PA, Charlot S, Chevallard J, D'Eugenio F, Egami E, Johnson BD, Jones GC, Lyu J, Maiolino R, Pérez-González PG, Rieke MJ, Robertson B, Saxena A, Scholtz J, Shivaei I, Sun F, Tacchella S, Whitler L, Williams CC, Willmer CNA, Willott C, Witstok J, Zhu Y.   +33 more
europepmc   +1 more source

Observational Properties of Primordial Stellar Populations [PDF]

, 2002
N. Panagia, M. Stiavelli, Henry C. Ferguson, H. S. Stockman   +3 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Potential impact of the Sagittarius dwarf galaxy on the formation of young O-rich stars. [PDF]

Nat Commun
Sun T, Bi S, Chen X, Chen Y, Lu YL, Liu C, Buck T, Zhang X, Li T, Li Y, Wu Y, Ge Z, Ye L.   +12 more
europepmc   +1 more source

BREATHING FIRE: HOW STELLAR FEEDBACK DRIVES RADIAL MIGRATION, RAPID SIZE FLUCTUATIONS, AND POPULATION GRADIENTS IN LOW-MASS GALAXIES [PDF]

, 2016
Kareem El-Badry, Andrew Wetzel, Marla Geha, Philip F. Hopkins, Dusan Kereš, T. K. Chan, Claude-André Faucher-Giguère   +6 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The Potential Impact of Sotatercept on Long-Term Disability in Commercially Insured Patients with Pulmonary Arterial Hypertension in the United States: An Exercise in Actuarial Modeling. [PDF]

Adv Ther
Watzker A, Alsumali A, Ferro C, Li XJ, Dieguez G, Park C, Chevure J, Lautsch D, El-Kersh K.   +8 more
europepmc   +1 more source

Ancient stellar populations in the outskirts of nearby grand-design spirals: Investigation of their star formation histories [PDF]

Cristina Maria Lofaro, Laura Bisigello, A Enia, Ariel Werle, Laura Bisigello, P. Cassata, V. Casasola, A. Renzini, Letizia Scaloni, Alessandro Bianchetti   +9 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Expanding Targeted Instrumentation for Discovery Applications: Complement Reporter Ion Quantification with a Quadrupole-Ion Trap Instrument. [PDF]

J Proteome Res
Cruz ER, Johnson ANT, Pujari V, Zhang Q, Nguyen T, Stadlmeier M, Wang J, Jacob CC, McAlister GC, Remes PM, Wühr M.   +10 more
europepmc   +1 more source