Results 101 to 110 of about 220,237 (344)

Architectures of Planetary Systems. II. Trends with Host Star Mass and Metallicity

The Astronomical Journal
The current census of planetary systems displays a wide range of architectures. Extending earlier work, this paper investigates the correlation between our classification framework for these architectures and host stellar properties.
Alex R. Howe, Juliette C. Becker, Fred C. Adams   +2 more
doaj   +1 more source

Dissipative transformation of non-nucleated dwarf galaxies into nucleated systems

, 2006
Recent photometric observations by the {\it Hubble Space Telescope (HST)} have revealed the physical properties of stellar galactic nuclei in nucleated dwarf galaxies in the Virgo cluster of galaxies.
Binggeli B., Kenji Bekki, Larson R. B., Warrick J. Couch, Yasuhiro Shioya   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A Data-driven Spectral Model of Main-sequence Stars in Gaia DR3

The Astrophysical Journal
Precise spectroscopic classification of planet hosts is an important tool of exoplanet research at both the population and individual system level.
Isabel Angelo, Megan Bedell, Erik Petigura, Melissa Ness   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Constraints on White Dwarf Hydrogen Layer Masses Using Gravitational Redshifts

The Astrophysical Journal
The hydrogen envelope is the outermost layer of a DA white dwarf; it makes up the entirety of the stellar photosphere, and yet its typical extent is difficult to model theoretically and remains poorly observationally constrained.
Stefan M. Arseneau, J. J. Hermes, Maria E. Camisassa, Roberto Raddi, Evan B. Bauer   +4 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Dependence of Planet Populations on Stellar Mass and Metallicity: A Pebble-accretion-based Planet Population Synthesis Model

The Astrophysical Journal
The formation and evolution of planetary systems are linked to their host stellar environment. In this study, we employ a pebble-accretion-based planet population synthesis model to explore the correlation between planetary properties and stellar mass ...
Mengrui Pan, Beibei Liu, Linjie Jiang, Jiwei Xie, Wei Zhu, Ignasi Ribas   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Seeking Spectroscopic Binaries with Data-driven Models

The Astrophysical Journal
Data-driven stellar classification has a long and important history in astronomy, dating as far back as Annie Jump Cannon’s “by-eye” classifications of stars into spectral types, still used today.
Isabel Angelo, Erik Petigura, Megan Bedell   +2 more
doaj   +1 more source