Results 101 to 110 of about 115,605 (291)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Anchoring Stellar Age Indicators: A Cross Calibration of [C/N] and Gyrochronology Ages via the Age–Velocity Dispersion Relation

The Astronomical Journal
Determining stellar ages is challenging, as it depends on other stellar parameters in a nonlinear way and often relies on stellar evolution models to infer the underlying relation between these parameters and age. This complexity increases when comparing
Yuxi(Lucy) Lu, Marc H. Pinsonneault, Yuan-Sen Ting, Phil R. Van-Lane, John D. Roberts, Jamie Tayar, Alexander Stone-Martinez, Amanda L. Ash   +7 more
doaj   +1 more source

Extended main sequences in star clusters

Fundamental Research
Extended main sequences (eMSs) and extended main-sequence turn-offs (eMSTOs) are fascinating phenomena that are routinely observed in star clusters. These phenomena strongly challenge the current canonical “simple stellar population” picture of star ...
Chengyuan Li, Antonino P. Milone, Weijia Sun, Richard de Grijs   +3 more
doaj   +1 more source

Revisiting the connection between magnetic activity, rotation period, and convective turnover time for main-sequence stars

, 2018
The connection between stellar rotation, stellar activity, and convective turnover time is revisited with a focus on the sole contribution of magnetic activity to the Ca II H&K emission, the so-called excess flux, and its dimensionless indicator R$^{+}_{\
Mittag, M., Schmitt, J. H. M. M., Schröder, K. -P.   +2 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

The California Legacy Survey. VI. The Fate of Activity Cycles in Sun-like Stars

The Astronomical Journal
We analyze the spectra of 91 solar-type G- and K-type main-sequence dwarfs in the solar neighborhood to assess activity trends with stellar properties.
Howard Isaacson, Stephen R. Kane, Brad Carter, Andrew W. Howard   +3 more
doaj   +1 more source

Stellar ages and stellar rotation

, 2016
Stellar ages will play a big role in the next generation of astronomy. Useful to exoplaneteers and galactic archaeologists alike, this relatively under-exploited stellar property is currently limited by the precision of dating techniques. The work presented in this thesis contributes incrementally to a greater understanding of rotation period decay in ...
openaire   +2 more sources

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Rapidly rotating red giants

EPJ Web of Conferences, 2017
Stellar oscillations give seismic information on the internal properties of stars. Red giants are targets of interest since they present mixed modes, wich behave as pressure modes in the convective envelope and as gravity modes in the radiative core ...
Gehan Charlotte, Mosser Benoît, Michel Eric   +2 more
doaj   +1 more source