Results 211 to 220 of about 1,192 (260)

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

High-temperature ²⁰⁵Tl decay clarifies ²⁰⁵Pb dating in early Solar System. [PDF]

Nature
Leckenby G, Sidhu RS, Chen RJ, Mancino R, Szányi B, Bai M, Battino U, Blaum K, Brandau C, Cristallo S, Dickel T, Dillmann I, Dmytriiev D, Faestermann T, Forstner O, Franczak B, Geissel H, Gernhäuser R, Glorius J, Griffin C, Gumberidze A, Haettner E, Hillenbrand PM, Karakas A, Kaur T, Korten W, Kozhuharov C, Kuzminchuk N, Langanke K, Litvinov S, Litvinov YA, Lugaro M, Martínez-Pinedo G, Menz E, Meyer B, Morgenroth T, Neff T, Nociforo C, Petridis N, Pignatari M, Popp U, Purushothaman S, Reifarth R, Sanjari S, Scheidenberger C, Spillmann U, Steck M, Stöhlker T, Tanaka YK, Trassinelli M, Trotsenko S, Varga L, Vescovi D, Wang M, Weick H, Yagüe Lopéz A, Yamaguchi T, Zhang Y, Zhao J.   +58 more
europepmc   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

The spectral evolution of white dwarfs: where do we stand? [PDF]

Astrophys Space Sci
Bédard A.
europepmc   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Binary progenitor systems for Type Ic supernovae. [PDF]

Nat Commun
Solar M, Michałowski MJ, Nadolny J, Galbany L, Hjorth J, Zapartas E, Sollerman J, Hunt L, Klose S, Koprowski M, Leśniewska A, Małkowski M, Nicuesa Guelbenzu AM, Ryzhov O, Savaglio S, Schady P, Schulze S, de Ugarte Postigo A, Vergani SD, Watson D, Wróblewski R.   +20 more
europepmc   +1 more source

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

One month convection timescale on the surface of a giant evolved star. [PDF]

Nature
Vlemmings W, Khouri T, Bojnordi Arbab B, De Beck E, Maercker M.   +4 more
europepmc   +1 more source

A cosmic-ray loaded nascent outflow driven by a massive star cluster. [PDF]

Nat Commun
Lemoine-Goumard M, Härer L, Mohrmann L, Bernet R, Hinton J, Peron G, Reville B, Tibaldo L, Vieu T.   +8 more
europepmc   +1 more source