Results 41 to 50 of about 2,161,661 (318)

The Combined Effect of Obesity and Contraceptive Use on Pulmonary Embolism in Adolescent Females Residing in the United States

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Combined oral contraceptive (COC) use in obese adult women dramatically increases the relative risk of developing a pulmonary embolism (PE). The risk of a PE in obese adolescent females taking contraceptives is currently unknown. The purpose of this investigation was to determine the effect of body mass index (BMI) and contraceptive
John Puetz, Joanne Salas
wiley   +1 more source

The role of microRNAs in stemness of cancer stem cells

open access: yesOncology Reviews, 2013
Cancer is one of the most important diseases of humans, for which no cure has been found so far. Understanding the causes of cancer can pave the way for its treatment. Alteration in genetic elements such as oncogenes and tumor suppressor genes results in cancer.
Seyed Mohammad Ali Hosseini Rad   +5 more
openaire   +3 more sources

Deconstructing stemness [PDF]

open access: yesThe EMBO Journal, 2005
Stem cells are unique in their capacity to self-renew and generate differentiated progeny to maintain tissues throughout life. A common molecular program for stem cells has remained elusive. We discuss what the molecular logic of stemness may be. We suggest that it may not be coupled to distinct cellular properties such as self-renewal or multipotency,
Harald, Mikkers, Jonas, Frisén
openaire   +2 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts. [PDF]

open access: yes, 2013
Copyright: 2013 Hermann et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Tunici, P   +51 more
core   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells [PDF]

open access: yes, 2012
Widera D, Hauser S, Kaltschmidt C, Kaltschmidt B. Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy Research International.
Hauser, Stefan   +4 more
core   +2 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier   +10 more
wiley   +1 more source

Ethical and Regulatory Challenges with Autologous Adult Stem Cells:A Comparative Review of International Regulations [PDF]

open access: yes, 2015
Cell and tissue-based products, such as autologous adult stem cells, are being prescribed by physicians across the world for diseases and illnesses that they have neither been approved for or been demonstrated as safe and effective in formal clinical ...
Lysaght, T   +9 more
core   +1 more source

The Enhancement of Arabic Stemming by Using Light Stemming and Dictionary-Based Stemming

open access: yesJournal of Software Engineering and Applications, 2011
Word stemming is one of the most important factors that affect the performance of many natural language processing applications such as part of speech tagging, syntactic parsing, machine translation system and information retrieval systems. Computational stemming is an urgent problem for Arabic Natural Language Processing, because Arabic is a highly ...
Yasir Alhanini, Mohd Juzaiddin Ab Aziz
openaire   +2 more sources

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