Results 161 to 170 of about 1,463,285 (410)

Tyrosine kinase inhibitors improve long-term outcome of allogeneic hematopoietic stem cell transplantation for adult patients with philadelphia chromosome positive acute lymphoblastic leukemia [PDF]

, 2015
This study aimed to determine the impact of tyrosine kinase inhibitors given pre- and post-allogeneic stem cell transplantation on long-term outcome of patients allografted for Philadelphia chromosome-positive acute lymphoblastic leukemia.
Aljurf, M. (Mahmoud), Beckers, M.M. (Marielle M.), Brissot, E. (Eolia), Cornelissen, J.J. (Jan), Craddock, C.F. (Charles), Esteve, J. (Jordi), Finke, J. (Jürgen), Gürman, G. (Günhan), Kröger, N. (Nicolaus), Labopin, M. (Myriam), Lenhoff, S. (S.), Mohty, M. (Mohamad), Nagler, A. (Arnon), Ossenkoppele, G.J. (Gert), Ottmann, O.G., Potter, M. (M.), Rambaldi, A. (Alessandro), Russell, N.H. (Nigel H.), Socié, G. (Gerard), Volin, L. (Liisa), Yakoub-Agha, I. (Ibrahim)   +20 more
core   +1 more source

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

FXa‐Responsive Hydrogels to Craft Corneal Endothelial Lamellae

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
This study introduces a sacrificial, multicomponent biohybrid hydrogel system enabling stable scaffold‐free tissue engineering. Its efficacy is demonstrated through the ex vivo development, detachment, and transplantation of human corneal endothelial lamellae, achieving clinically relevant sizes for Descemet Membrane Endothelial Keratoplasty.
Mikhail V. Tsurkan, Juliane Bessert, Rabea Selzer, Sarah D. Tsurkan, Dagmar Pette, Manfred F. Maitz, Petra B. Welzel, Carsten Werner   +7 more
wiley   +1 more source

Effect of Erythropoietin on Proliferation of Erythroid Stem Cells in the Absence of Transplantable Colony-forming Units [PDF]

, 1970
Kurt R. Reißmann, Sommart Samorapoompichit   +1 more
openalex   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

The Pattern of Stem Cell Repopulation in Heavily Irradiated Mice Receiving Transplants of Fetal Liver [PDF]

, 1970
B. Kubanek, N. J. Rencricca, Adolfo Porcellini, Donald R. Howard, Frederick Stohlman   +4 more
openalex   +1 more source

Lenalidomide after stem-cell transplantation for multiple myeloma.

New England Journal of Medicine, 2012
BACKGROUND Data are lacking on whether lenalidomide maintenance therapy prolongs the time to disease progression after autologous hematopoietic stem-cell transplantation in patients with multiple myeloma.
P. McCarthy, K. Owzar, C. Hofmeister, D. Hurd, H. Hassoun, P. Richardson, S. Giralt, E. Stadtmauer, D. Weisdorf, R. Vij, J. Moreb, N. Callander, K. van Besien, T. Gentile, L. Isola, R. Maziarz, D. Gabriel, A. Bashey, H. Landau, T. Martin, M. Qazilbash, D. Levitan, B. Mcclune, R. Schlossman, V. Hárs, John Postiglione, Chen Jiang, E. Bennett, S. Barry, L. Bressler, M. Kelly, Michele Seiler, C. Rosenbaum, P. Hari, M. Pasquini, M. Horowitz, T. Shea, S. Devine, K. Anderson, C. Linker   +39 more
semanticscholar   +1 more source

Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. [PDF]

, 2016
Urea cycle disorders are incurable enzymopathies that affect nitrogen metabolism and typically lead to hyperammonemia. Arginase deficiency results from a mutation in Arg1, the enzyme regulating the final step of ureagenesis and typically results in ...
Angarita, Stephanie Ak, Byrne, James A, Cederbaum, Stephen D, Chang, Katherine M, Gilmore, W Blake, Hermann, Kip, Lam, Alex K, Lee, Patrick C, Lipshutz, Gerald S, Pyle, April D, Schoenberg, Benjamen E, Tang, Jonathan K, Truong, Brian, Vega-Crespo, Agustin, Wininger, Austin E   +14 more
core   +3 more sources

Enhanced Bioprinting of 3D Corneal Stroma Patches with Reliability, Assessing Product Consistency and Quality through Optimized Electron Beam Sterilization

Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.
This study optimizes sterilization methods for bioprinted 3D corneal stroma patches made from cornea‐derived decellularized extracellular matrix (Co‐dECM) hydrogels and human keratocytes. It demonstrates the superiority of electron beam sterilization in preserving the mechanical, biochemical, and immunomodulatory properties of hydrogels, ensuring ...
Jungbin Yoon, Yeon‐ju Lee, Minji Kim, Ju Young Park, Jinah Jang   +4 more
wiley   +1 more source

Lymphohemopoietic reconstitution using wheat germ agglutinin-positive hemopoietic stem cell transplantation within but not across the major histocompatibility antigen barriers. [PDF]

, 1993
N Badri, Robert A. Good
openalex   +2 more sources