Results 171 to 180 of about 1,463,285 (410)
Molecular Therapy: Methods & Clinical Development, 2020 Treatment with axicabtagene ciloleucel (Axi-cel) CD19-CAR-T (chimeric antigen receptor T) cells has been approved for refractory/relapsed diffuse large B cell lymphoma (DLBCL) and primary mediastinal large B cell lymphoma (PMBCL).
Boris Fehse +7 more
doaj
Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging. [PDF]
, 1978 David Harrison +2 more
openalex +1 more source
Lenalidomide maintenance after stem-cell transplantation for multiple myeloma.
New England Journal of Medicine, 2012 BACKGROUND High-dose chemotherapy with autologous stem-cell transplantation is a standard treatment for young patients with multiple myeloma. Residual disease is almost always present after transplantation and is responsible for relapse.
M. Attal +22 more
semanticscholar +1 more source
a randomized, open, multicenter phase III trial of lenalidomide/dexamethasone versus lenalidomide/dexamethasone plus subsequent autologous stem cell transplantation and lenalidomide maintenance in patients with relapsed multiple myeloma [PDF]
, 2016 Background Despite novel therapeutic agents, most multiple myeloma (MM) patients eventually relapse. Two large phase III trials have shown significantly improved response rates (RR) of lenalidomide/dexamethasone compared with placebo/dexamethasone in ...
Baertsch, Marc-Andrea +28 more
core +1 more source
Kidney Fibrosis In Vitro and In Vivo Models: Path Toward Physiologically Relevant Humanized Models
Advanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.This review discusses kidney diseases with a focus on kidney fibrosis and the models currently used. It highlights the limitations of animal and 2D in vitro models in replicating human kidney anatomy and physiology. Consequently, there is a significant need for humanized 3D in vitro models, such as 3D cell aggregates, membranes and hydrogels, on‐chip ...
Gabriele Addario +2 more
wiley +1 more source
Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy [PDF]
, 1988 Anne Kessinger +4 more
openalex +1 more source
Brain : a journal of neurology, 2015 Haematopoietic stem cell transplantation has been proposed as treatment for mitochondrial neurogastrointestinal encephalomyopathy, a rare fatal autosomal recessive disease due to TYMP mutations that result in thymidine phosphorylase deficiency.
J. Halter +34 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon +6 more
wiley +1 more source
Stem Cells: The Good, the Bad and the Ugly [PDF]
arXiv, 2016 Cancer stem cells are controlled by developmental networks that are often topologically indistinguishable from normal, healthy stem cells. The question is why cancer stem cells can be both phenotypically distinct and have morphological effects so different from normal stem cells.
arxiv