Results 261 to 270 of about 5,922,427 (309)

Limbal Stem-Cell Transplantation

International Ophthalmology Clinics, 1999
Cornea epithelium is subject to constant trauma and shedding of the surface epithelium, and replenishment is from epithelial cells beneath and peripheral to the central desquamating epithelium. The origin of the corneal epithelium appears to reside in the crypts of Vogt, where a population of "immortal" stem cells resides, possessing enormous potential
E K, Akpek, C S, Foster
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Fetal stem-cell transplantation

Best Practice & Research Clinical Obstetrics & Gynaecology, 2008
Fetal stem-cell transplantation is an attractive approach to the treatment of a variety of hematological, metabolic and immunological diseases before birth. The possibility of delivering a large number of cells in an early stage of life, and of taking advantage of normal fetal stem-cell migration and development, is promising.
Eleonor, Tiblad, Magnus, Westgren
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HIV and Stem Cell Transplantation

Current Infectious Disease Reports, 2014
In human immunodeficiency virus (HIV)-infected persons, the incidence of hematologic malignancies, including leukemia and lymphoma, is increased despite the use of successful antiretroviral therapy. Hematopoietic stem cell transplantation (SCT) is emerging as a safe and effective therapy for HIV-infected persons with hematologic malignancies ...
Ignacio A, Echenique, George E, Nelson, Valentina, Stosor, Christine M, Durand   +3 more
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Intestinal stem cell transplantation

Journal of Gastroenterology, 2016
Organoid technologies to expand intestinal epithelial cells are gaining increasing attention as a useful tool to investigate many aspects of intestinal epithelial biology and pathology. One important application of organoid systems would be to use intestinal epithelial cells expanded in culture for following transplantation experiments. In this article,
Tetsuya, Nakamura, Mamoru, Watanabe
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Immunomodulation in stem-cell transplantation

Current Opinion in Pharmacology, 2002
Acute graft-versus-host disease is a complication that affects 30-60% of patients undergoing allogeneic stem-cell transplantation. The standard for prophylaxis for graft-versus-host disease has historically been the combination of cyclosporine and methotrexate.
Reem A, Abo-Zena, Mitchell E, Horwitz
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Role of Stem Cell Transplantation

Hematology/Oncology Clinics of North America, 2007
Hematopoietic stem cell transplantation (SCT) was introduced in the treatment of multiple myeloma in the 1980s. In the autologous setting, the use of peripheral blood stem cells instead of bone marrow has markedly improved feasibility. In fit patients who have normal renal function and are younger than 65 years of age, randomized studies have shown the
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In Utero Stem Cell Transplantation

Seminars in Reproductive Medicine, 2006
Successful in utero stem cell transplantations with hematopoietic or other stem cells should represent a major step forward in the management of patients with congenital, hematological, metabolic, and immunological disorders. The possibility of performing cell transplantations with stem cells across histoincompatibility barriers without chemotherapy ...
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Stem Cell Transplantation for Myelodysplasia

2001
The natural course of MDS varies considerably depending upon patient age and findings at the time of diagnosis. Life expectancy ranges from years in early stages to only a few months in advanced stages. The disease can rapidly progress to acute leukemia, and the prognosis for patients with advanced MDS (RAEB, RAEBT) and therapy-related (secondary) MDS ...
H G, Klingemann, H J, Deeg
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Stem cell transplantation for hemoglobinopathies

Current Opinion in Pediatrics, 2003
Hereditary anemias caused by beta-thalassemia and sickle cell disease are the most common genetic diseases worldwide. Supportive therapies such as chronic lifelong transfusions, iron chelation for thalassemia, and transfusions or hydroxyurea for sickle cell anemia have significantly ameliorated clinical manifestations of these diseases but cannot ...
Javid, Gaziev, Guido, Lucarelli
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Nonmyeloablative stem cell transplants

Current Opinion in Hematology, 1999
Allogeneic stem cell transplantation (SCT) is a curative procedure in a number of hematologic malignancies, but its efficacy is limited by its toxicity, much of which is consequent upon the myeloablative conditioning regimens currently used. The recent demonstration that an immunologically mediated graft-versus-leukemia effect plays a central role in ...
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