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Klinische Pädiatrie, 2013
Stem cell transplantation in pediatric patients with leukemia has been a matter of debate since the first successful transplantation in a child with aplastic anemia in Germany in 1975. Since then, there has been a long way to implement fully stem cell transplantation strategies into the treatment studies organized within BFM Groups for first line or ...
T. Klingebiel +3 more
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Stem cell transplantation in pediatric patients with leukemia has been a matter of debate since the first successful transplantation in a child with aplastic anemia in Germany in 1975. Since then, there has been a long way to implement fully stem cell transplantation strategies into the treatment studies organized within BFM Groups for first line or ...
T. Klingebiel +3 more
+8 more sources
Allogeneic Stem Cell Transplantation
Transplantation Proceedings, 2005Allogeneic stem cell transplantation (HSCT) requires the harvest of an adequate number of stem cells (SC) from a histocompatible donor and their infusion into a patient following a conditioning regimen. During the past 35 years, the role of HSCT has changed from an experimental procedure for terminally ill patients to a curative treatment.
BOSI, ALBERTO, BARTOLOZZI B, GUIDI S.
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Spermatogonial stem cell transplantation
Molecular and Cellular Endocrinology, 2000The development of the spermatogonial transplantation technique has given new impetus to research on spermatogonial stem cells. Possibilities opened by this technique include: (a) New ways to study fundamental aspects of spermatogenesis; (b) Generation of transgenic large domestic animals; (c) Protection of (young) male cancer patients from infertility
Laura B. Creemers +4 more
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Stem Cells in Cell Transplantation
Stem Cells and Development, 2006This commentary documents the increased number of stem cell-related research reports recently published in the cell transplantation field in the journal Cell Transplantation. The journal covers a wide range of issues in cell-based therapy and regenerative medicine and is attracting clinical and preclinical articles from around the world.
Paul R. Sanberg +2 more
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Limbal Stem-Cell Transplantation
International Ophthalmology Clinics, 1999Cornea epithelium is subject to constant trauma and shedding of the surface epithelium, and replenishment is from epithelial cells beneath and peripheral to the central desquamating epithelium. The origin of the corneal epithelium appears to reside in the crypts of Vogt, where a population of "immortal" stem cells resides, possessing enormous potential
Foster Cs, Akpek Ek
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Stem cell transplantation [PDF]
The Lancet, 2001 The principle of cell therapy is simple—to restore brain function by transplantation of new neurons, which replace those lost through damage or disease. However, in view of the complexity of human brain circuitry and function, this prospect might seem remote.
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Fetal stem-cell transplantation
Best Practice & Research Clinical Obstetrics & Gynaecology, 2008Fetal stem-cell transplantation is an attractive approach to the treatment of a variety of hematological, metabolic and immunological diseases before birth. The possibility of delivering a large number of cells in an early stage of life, and of taking advantage of normal fetal stem-cell migration and development, is promising.
Magnus Westgren, Eleonor Tiblad
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Haemopoietic stem cell transplantation
2010Abstract Haemopoietic stem cells (HSCs) give rise to the blood cell lineages and the cells of the immune system, and their transplantation may be an appropriate part of the management of conditions including (1) malignant haematological disorders (e.g. leukaemia, lymphoma, myeloma); (2) bone marrow failure syndromes (e.g.
E.C. Gordon-Smith, Emma Morris
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HIV and Stem Cell Transplantation [PDF]
Current Infectious Disease Reports, 2014 In human immunodeficiency virus (HIV)-infected persons, the incidence of hematologic malignancies, including leukemia and lymphoma, is increased despite the use of successful antiretroviral therapy. Hematopoietic stem cell transplantation (SCT) is emerging as a safe and effective therapy for HIV-infected persons with hematologic malignancies ...
Ignacio A. Echenique +3 more
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In Utero Stem Cell Transplantation
Seminars in Reproductive Medicine, 2006Successful in utero stem cell transplantations with hematopoietic or other stem cells should represent a major step forward in the management of patients with congenital, hematological, metabolic, and immunological disorders. The possibility of performing cell transplantations with stem cells across histoincompatibility barriers without chemotherapy ...
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