Results 51 to 60 of about 1,446,025 (307)

The Role of Allogeneic Transplantation in Chronic Myeloid Leukemia in 2023: A Case-Based Concise Review

Hemato, 2023
Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML), granting patients a life expectancy close to that of the normal population and, in a subset of patients, the possibility to discontinue therapy ...
Mario Tiribelli, Giuseppe Petruzzellis, Giulia Battaglia, Martina Pucillo, Marta Lisa Battista, Michela Cerno, Antonella Geromin, Gabriele Facchin, Umberto Pizzano, Daniela Damiani, Renato Fanin, Francesca Patriarca   +11 more
doaj   +1 more source

Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. [PDF]

Blood, 1998
S. Slavin, A. Nagler, E. Naparstek, Yossi Kapelushnik, M. Aker, G. Cividalli, G. Váradi, M. Kirschbaum, A. Ackerstein, S. Samuel, A. Amar, C. Brautbar, O. Ben‐Tal, A. Eldor, R. Or   +14 more
semanticscholar   +2 more sources

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]

, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
A Dar, A D’Souza, A Foudi, A Nagler, A Peled, AM Greenbaum, AW Roberts, B Nervi, CC Bleul, CL Semerad, D Obrecht, DE Harrison, F Ferraro, F Liu, GA Velders, GL Uy, H Balaguer, H Bonig, H Bonig, H Bonig, H Bonig, H Bonig, HE Broxmeyer, IG Winkler, JP Levesque, JP Levesque, K Balabanian, MA Pulsipher, MA Ryan, MJ Christopher, MM Mueller, MP Rettig, MZ Ratajczak, N Amariglio, P Anderlini, P Anderlini, P Anderlini, S Akizuki, SJ DeMarco, SJ Szilvassy, SM Devine, SP Fricker, T Lapidot, TA Lane, V Saini, WC Liles, Y Katayama, Y Takamatsu   +47 more
core   +1 more source

Do high-volume centers really save more lives? A call for scientific rigor and transparency. Response to Comment on: Does size matter? Center-specific characteristics and survival after allogeneic hematopoietic cell transplantation for acute myeloid leukemia: an analysis of the German Registry for Stem Cell Transplantation and Cell Therapy

Haematologica
Not available.
Wolfgang Bethge, Peter Dreger, German Working Group for Hematopoietic Stem Cell Transplantation and Cellular Therapy e.V. (DAG-HSZT) - German Registry for Hematopoietic Stem Cell Transplantation and Cell Therapy (DRST)   +2 more
doaj   +1 more source

Tyrosine kinase inhibitors improve long-term outcome of allogeneic hematopoietic stem cell transplantation for adult patients with philadelphia chromosome positive acute lymphoblastic leukemia [PDF]

, 2015
This study aimed to determine the impact of tyrosine kinase inhibitors given pre- and post-allogeneic stem cell transplantation on long-term outcome of patients allografted for Philadelphia chromosome-positive acute lymphoblastic leukemia.
Aljurf, M. (Mahmoud), Beckers, M.M. (Marielle M.), Brissot, E. (Eolia), Cornelissen, J.J. (Jan), Craddock, C.F. (Charles), Esteve, J. (Jordi), Finke, J. (Jürgen), Gürman, G. (Günhan), Kröger, N. (Nicolaus), Labopin, M. (Myriam), Lenhoff, S. (S.), Mohty, M. (Mohamad), Nagler, A. (Arnon), Ossenkoppele, G.J. (Gert), Ottmann, O.G., Potter, M. (M.), Rambaldi, A. (Alessandro), Russell, N.H. (Nigel H.), Socié, G. (Gerard), Volin, L. (Liisa), Yakoub-Agha, I. (Ibrahim)   +20 more
core   +1 more source

Fludarabine, cytarabine, and idarubicin with or without venetoclax in patients with relapsed/refractory acute myeloid leukemia

Haematologica, 2023
Treatment options for relapsed and refractory acute myeloid leukemia patients (R/R AML) are limited. This retrospective cohort study compares safety and efficacy of fludarabine, cytarabine, and idarubicin (FLA-IDA) without or with venetoclax (FLAVIDA ...
Rabia Shahswar, Gernot Beutel, Razif Gabdoulline, Adrian Schwarzer, Arnold Kloos, Christian Koenecke, Michael Stadler, Gudrun Gohring, Yvonne Lisa Behrens, Zhixiong Li, Louisa-Kristin Dallmann, Piroska Klement, Catherin Albert, Martin Wichmann, Yasmine Alwie, Axel Benner, Maral Saadati, Arnold Ganser, Felicitas Thol, Michael Heuser   +19 more
doaj   +1 more source

a randomized, open, multicenter phase III trial of lenalidomide/dexamethasone versus lenalidomide/dexamethasone plus subsequent autologous stem cell transplantation and lenalidomide maintenance in patients with relapsed multiple myeloma [PDF]

, 2016
Background Despite novel therapeutic agents, most multiple myeloma (MM) patients eventually relapse. Two large phase III trials have shown significantly improved response rates (RR) of lenalidomide/dexamethasone compared with placebo/dexamethasone in ...
Baertsch, Marc-Andrea, Fenk, Roland, Goerner, Martin, Goldschmidt, Hartmut, Graeven, Ullrich, Haenel, Mathias, Hielscher, Thomas, Hillengass, Jens, Ho, Anthony D., Hose, Dirk, Jauch, Anna, Klein, Stefan, Kunz, Christina, Lindemann, Hans W., Luntz, Steffen, Mai, Elias K., Martin, Hans, Merz, Maximilian, Nogai, Axel, Noppeney, Richard, Raab, Marc S., Reimer, Peter, Salwender, Hans, Scheid, Christof, Schlenzka, Jana, Schmidt-Hieber, Martin, Schmidt-Wolf, Ingo G. H., Weisel, Katja, Wuchter, Patrick   +28 more
core   +1 more source

Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantation

Haematologica
We compared long-term outcomes in 78 patients with steroid-refractory acute graft-versushost disease (SR-aGVHD) treated at the University Medical Center Hamburg, Germany between December 2015 and August 2022 who received either ruxolitinib alone (Ruxo ...
Iryna Lastovytska, Silke Heidenreich, Evgeny Klyuchnikov, Christian Niederwieser, Nico Gagelmann, Johanna Richter, Radwan Massoud, Kristin Rathje, Tetiana Perekhrestenko, Gaby Zeck, Catherina Lück, Dietlinde Janson, Christine Wolschke, Francis Ayuk, Nicolaus Kröger   +14 more
doaj   +1 more source

Human neural stem cell transplantation improves cognition in a murine model of Alzheimer’s disease

Scientific Reports, 2018
Stem cell transplantation offers a potentially transformative approach to treating neurodegenerative disorders. The safety of cellular therapies is established in multiple clinical trials, including our own in amyotrophic lateral sclerosis.
Lisa M. McGinley, Osama N. Kashlan, Elizabeth S. Bruno, Kevin S Chen, J. Hayes, Samy R. Kashlan, J. Raykin, K. Johe, G. Murphy, E. Feldman   +9 more
semanticscholar   +1 more source

Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients With Intestinal Failure. [PDF]

, 2016
: Intestinal failure is a rare life-threatening condition that results in the inability to maintain normal growth and hydration status by enteral nutrition alone.
Dunn, James CY, Hong, Sung Noh, Martín, Martín G, Stelzner, Matthias   +3 more
core   +1 more source