Results 61 to 70 of about 1,463,285 (410)

Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report

Bone Marrow Transplantation, 2017
Hematopoietic stem cell transplantation (HSCT) is an established procedure for many acquired and congenital disorders of the hematopoietic system. A record number of 42 171 HSCT in 37 626 patients (16 030 allogeneic (43%), 21 596 autologous (57%)) were ...
J. Passweg, H. Baldomero, Peter Bader, C. Bonini, R. Duarte, Carlo Dufour, A. Gennery, N. Kröger, J. Kuball, Francesco Lanza, Silvia Montoto, Arnon Nagler, John A. Snowden, J. Styczyński, M. Mohty   +14 more
semanticscholar   +1 more source

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell-Derived Self-Forming Retina. [PDF]

, 2015
Loss of photoreceptors due to retinal degeneration is a major cause of untreatable blindness. Cell replacement therapy, using pluripotent stem cell-derived photoreceptor cells, may be a feasible future treatment.
Ali, RR, Bainbridge, JW, Blackford, SJ, Gonzalez-Cordero, A, Han, YT, Lakowski, J, Naeem, A, Pearson, RA, Sowden, JC, Welby, E, West, EL   +10 more
core   +1 more source

Nanopore sequencing approach for immunoglobulin gene analysis in chronic lymphocytic leukemia

Scientific Reports, 2021
The evaluation of the somatic hypermutation of the clonotypic immunoglobulin heavy variable gene has become essential in the therapeutic management in chronic lymphocytic leukemia patients.
Crescenzio Francesco Minervini, Cosimo Cumbo, Immacolata Redavid, Maria Rosa Conserva, Paola Orsini, Antonella Zagaria, Luisa Anelli, Nicoletta Coccaro, Giuseppina Tota, Luciana Impera, Elisa Parciante, Francesco Tarantini, Annamaria Giordano, Giorgina Specchia, Pellegrino Musto, Francesco Albano   +15 more
doaj   +1 more source

Utilization of hematopoietic stem cell transplantation for the treatment of multiple myeloma: a Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus statement

Bone Marrow Transplantation, 2018
Over the last two decades, the utilization of various novel therapies in the upfront or salvage settings has continued to improve survival outcomes for patients with Multiple Myeloma (MM).
W. Gonsalves, F. Buadi, S. Ailawadhi, P. Bergsagel, Asher A. Chanan Khan, D. Dingli, A. Dispenzieri, R. Fonseca, S. Hayman, P. Kapoor, T. Kourelis, M. Lacy, J. Larsen, Eli Muchtar, C. Reeder, T. Sher, A. Stewart, R. Warsame, R. Go, R. Kyle, N. Leung, Yi Lin, J. Lust, S. Russell, S. Zeldenrust, A. Fonder, Y. Hwa, M. Hobbs, Angela Mayo, W. Hogan, S. Rajkumar, Shaji K. Kumar, M. Gertz, V. Roy   +33 more
semanticscholar   +1 more source

Erythropoietin in stem cell transplantation [PDF]

Bone Marrow Transplantation, 2001
Anemia is universal after allogeneic and autologous stem cell transplantation, with both increased red cell utilization and decreased production playing a role. This anemia sometimes is associated with a relative erythropoietin deficiency. In allogeneic stem cell transplantation, randomized trials have demonstrated improved erythropoiesis and a ...
Hillard M. Lazarus, Carole B. Miller
openaire   +3 more sources

Potential for Stem Cells Therapy in Alzheimer’s Disease: Do Neurotrophic Factors Play Critical Role? [PDF]

, 2017
Alzheimer’s disease (AD) is one of the most common causes of dementia. Despite several decades of research in AD, there is no standard disease- modifying therapy available and currentlyapproved drugs provide only symptomatic relief.
Anand, Akshay, Bali, Parul, Banik, Avijit, Lahiri, Debomoy K., Nehru, Bimla   +4 more
core   +2 more sources

Risk assessment for newly diagnosed, fit and young patients with Multiple Myeloma, in the era of novel treatment modalities: Are there any additional factors to be under consideration?

Hematology, Transfusion and Cell Therapy, 2022
Objective: Multiple myeloma (MM) is considered a disease of elderlies however, 35-40% of newly diagnosed MM (NDMM) patients (pts) are ≤60 years (ys) old.
Panayotis Kaloyannidis, Fatema Abdulla, Enas Mutahar, Haidar Hashim, Salman Harbi, Analie Estanislao, Solaf Ka   +6 more
doaj  

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2016
The timely reconstitution and regain of function of a donor-derived immune system is of utmost importance for the recovery and long-term survival of patients after allogeneic hematopoietic stem cell transplantation (HSCT).
J. Ogonek, Mateja Kralj Juric, Sakhila Ghimire, P. Varanasi, E. Holler, H. Greinix, E. Weissinger   +6 more
semanticscholar   +1 more source

Haploidentical Hematopoietic Stem-Cell Transplantation in Adults [PDF]

, 2011
Haploidentical hematopoietic stem-cell transplantation is an alternative transplant strategy for patients without an HLA-matched donor. Still, only half of patients who might benefit from transplantation are able to find an HLA-matched related or ...
Alshemmari, Salem, Ameen, Reem, Gaziev, Javid   +2 more
core   +3 more sources

IRF4 expression is low in Philadelphia negative myeloproliferative neoplasms and is associated with a worse prognosis

Experimental Hematology & Oncology, 2021
Interferon regulatory factor 4 (IRF4) is involved in the pathogenesis of various hematologic malignancies. Its expression has been related to the negative regulation of myeloid-derived suppressor cells (MDSCs) and the polarization of anti-inflammatory M2
Cosimo Cumbo, Francesco Tarantini, Luisa Anelli, Antonella Zagaria, Immacolata Redavid, Crescenzio Francesco Minervini, Nicoletta Coccaro, Giuseppina Tota, Alessandra Ricco, Elisa Parciante, Maria Rosa Conserva, Giorgina Specchia, Pellegrino Musto, Francesco Albano   +13 more
doaj   +1 more source