Results 201 to 210 of about 282,779 (307)

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

DIY liquid handling robots for integrated STEM education and life science research. [PDF]

open access: yesPLoS One, 2022
Li E   +7 more
europepmc   +1 more source

Storying the FEW Nexus: A Framework for Cultivating Place-Based Integrated STEM Education in Rural Schools

open access: yes
When education in STEM, social science, and the humanities are disconnected from each other and from place, it is inauthentic and nonresponsive to the lived experiences of people and communities.
Azano, Amy Price   +3 more
core   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

open access: yesAdvanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim   +7 more
wiley   +1 more source

Outcomes from a STEM Education Program for Elementary School Students in Medically Underserved Areas and Populations. [PDF]

open access: yesJ Cancer Educ
Statman MR   +12 more
europepmc   +1 more source

PlatypOUs-A Mobile Robot Platform and Demonstration Tool Supporting STEM Education. [PDF]

open access: yesSensors (Basel), 2022
Rácz M   +8 more
europepmc   +1 more source

Active Learning‐Accelerated Discovery of Fibrous Hydrogels with Tissue‐Mimetic Viscoelasticity

open access: yesAdvanced Functional Materials, EarlyView.
Active learning accelerates the design of fibrous hydrogels that mimic the viscoelasticity of native tissues. By integrating multi‐objective optimization and closed‐loop experimentation, this approach efficiently identifies optimal formulations from thousands of possibilities and decouples elasticity and viscosity. The resulting hydrogels offer tunable
Zhengkun Chen   +11 more
wiley   +1 more source

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