Results 51 to 60 of about 320,127 (267)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluation of morphological and production characteristics and nutritive value of 47 lucerne cultivars/lines in temperate Australia

open access: yesPlant Production Science, 2019
Forty-seven lucerne varieties/lines were examined to quantify their morphological, production characteristics, and nutritive values in southeastern Australia.
Lili Nan   +3 more
doaj   +1 more source

Antimicrobial Natural Cellulose Fibers from Hyptis suaveolens for Potential Biomedical and Textiles Applications

open access: yesJournal of Natural Fibers, 2021
In this research, tulsi (wild type) stalks were treated with NaOH to obtain natural cellulosic fibers. X-ray diffractions showed typical cellulose diffraction peak at 22.7°.
Vijaykumar Guna   +6 more
doaj   +1 more source

The Stem of Cancer [PDF]

open access: yesCancer Cell, 2009
Despite great advances in our understanding of tumor initiation and progression, the identity of the "cell of origin" of cancer remains elusive. Two recent publications provide experimental evidence that normal intestinal stem cells are the cells of origin of intestinal cancer in the mouse.
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Super Seven “S” Trends (SSST) that Shape the Future of Philippine Global Ports [PDF]

open access: yesTransNav
The paper presents the port investments and initiatives the Philippine Port Authority spearheaded, including financial performance and operational highlights.
Angelica Baylon
doaj   +1 more source

Stem cell therapy independent of stemness

open access: yesWorld Journal of Stem Cells, 2012
Mesenchymal stem cell (MSC) therapy is entering a new era shifting the focus from initial feasibility study to optimization of therapeutic efficacy. However, how MSC therapy facilitates tissue regeneration remains incompletely characterized. Consistent with the emerging notion that secretion of multiple growth factors/cytokines (trophic factors) by MSC
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy