Results 31 to 40 of about 344,696 (268)

The role of microRNAs in stemness of cancer stem cells

Oncology Reviews, 2013
Cancer is one of the most important diseases of humans, for which no cure has been found so far. Understanding the causes of cancer can pave the way for its treatment. Alteration in genetic elements such as oncogenes and tumor suppressor genes results in cancer.
Seyed Mohammad Ali Hosseini Rad, Mahsa Shanaki Bavarsad, Ehsan Arefian, Kaveh Jaseb, Mohammad Shahjahani, Najmaldin Saki   +5 more
openaire   +3 more sources

A Complete Assessment of the Emission Performance of an SI Engine Fueled with Methanol, Methane and Hydrogen

Energies
This study explores the potentiality of low/zero carbon fuels such as methanol, methane and hydrogen for motor applications to pursue the goal of energy security and environmental sustainability.
Francesco Catapano, Silvana Di Iorio, Agnese Magno, Paolo Sementa, Bianca Maria Vaglieco   +4 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Enhanced Quasi-One-Dimensional Modeling and Design Performance Assessment of an ORC with Radial Turbine for Waste Heat Recovery

Energies
Organic Rankine Cycles (ORCs) are widely recognized as an effective solution for waste heat recovery (WHR). However, the design and optimization of these systems must address the tradeoff between computational efficiency and the need to capture complex ...
Raffaele Carandente, Alessandro di Gaeta, Veniero Giglio, Fabrizio Reale   +3 more
doaj   +1 more source

Influence of grape maturity and prefermentative cluster treatment of the Grenache cultivar on wine composition and quality

OENO One, 2016
This work studied how different grape maturity levels and cluster treatments affect the color and phenolic composition of Grenache wines. Specifically, five treatments were undertaken at a microvinification scale for three maturity levels : Control ...
Olga Pascual, Jeanette Ortiz, Maruxa Roel, Nikolaos Kontoudakis, Mariona Gil, Sergio Gómez-Alonso, Esteban García-Romero, Joan Miquel Canals, Isidro Hermosín-Gutíerrez, Fernando Zamora   +9 more
doaj   +1 more source

Ethanolic Extracts of Six Cultivated Mushrooms as a Source of Bioactive Compounds

Applied Sciences, 2023
Freeze-dried stems and caps of six cultivated mushroom species, namely Agaricus bisporus (white) Agaricus bisporus (brown), Lentinula edodes, Pholiota nameko, Pleurotus eryngii and Pleurotus ostreatus were subjected to ethanolic extraction.
Wojciech Radzki, Krzysztof Tutaj, Katarzyna Skrzypczak, Monika Michalak-Majewska, Waldemar Gustaw   +4 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

System Design and Stress–Strain Analysis for Cranking and Motoring Small-Size Engines

Designs
The characterization of small-size engines requires dedicated rigs that are usually used for loading the power unit. Adding the possibility of motoring the engine is an important advantage that allows more detailed information on operating ...
Giovanni Cecere, Adrian Irimescu, Simona Silvia Merola   +2 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Deconstructing stemness [PDF]

The EMBO Journal, 2005
Stem cells are unique in their capacity to self-renew and generate differentiated progeny to maintain tissues throughout life. A common molecular program for stem cells has remained elusive. We discuss what the molecular logic of stemness may be. We suggest that it may not be coupled to distinct cellular properties such as self-renewal or multipotency,
Harald, Mikkers, Jonas, Frisén
openaire   +2 more sources