Results 61 to 70 of about 704,886 (359)

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

NUMERICAL STUDY OF THE STRUCTURE AND LOCAL TURBULIZATION OF THE FLOW IN A BLOOD VESSEL WITH A ONE-SIDE STENOSIS

open access: yesSt. Petersburg Polytechnical University Journal: Physics and Mathematics, 2021
Results of large eddy simulation of three-dimensional flow in a model of the blood vessel with a one-side 70% stenosis at a Reynolds number of 1800 are presented. The Germano-Lilly model was used for subgrid viscosity evaluation.
Gataulin Yakov, Smirnov Evgeny
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Micropolar fluid flow through a stenosed bifurcated artery

open access: yesNonlinear Analysis, 2017
The aim of this article is to investigate the blood flow in bifurcated artery with mild stenosis taking blood as a micropolar fluid. The arteries, forming bifurcation are taken to be symmetric and straight cylinders of finite length.
Darbhasayanam Srinivasacharya   +1 more
doaj   +1 more source

Diaspirin cross-linked hemoglobin fails to improve left ventricular diastolic function after fluid resuscitation from hemorrhagic shock [PDF]

open access: yes, 2001
In severe hemorrhagic shock, left ventricular (LV) diastolic dysfunction is an early sign of cardiac failure due to compromised myocardial oxygenation.
Habler, Oliver   +4 more
core   +1 more source

Coronary atherosclerosis scoring with semiquantitative CCTA risk scores for prediction of major adverse cardiac events: Propensity score-based analysis of diabetic and non-diabetic patients. [PDF]

open access: yes, 2020
AIMS:We aimed to compare semiquantitative coronary computed tomography angiography (CCTA) risk scores - which score presence, extent, composition, stenosis and/or location of coronary artery disease (CAD) - and their prognostic value between patients ...
Achenbach, Stephan   +37 more
core   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu   +4 more
wiley   +1 more source

What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque?

open access: yesMedicina
Background and Objectives: Unstable atherosclerotic plaque in the arteries is one of the main risk factors for cerebral ischemia. Duplex ultrasound is a frequently used diagnostic method, but it has some limitations for microvascularization and ...
Andrejs Lioznovs   +4 more
doaj   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

open access: yesAdvanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter   +5 more
wiley   +1 more source

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