Results 81 to 90 of about 136,626 (309)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A review on flicker-free ac-dc LED drivers for single-phase and three-phase ac power grids [PDF]

open access: yes, 2019
Light-Emitting Diodes (LEDs) are coming strongly into the lighting market due to their advantages over conventional lighting solutions: energy efficient, controllable in both light and color, long lifetime, lack of a warm-up period and high power density.
Arias Pérez de Azpeitia, Manuel   +5 more
core   +2 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Mitigating Voltage Drop and Excessive Step-Voltage Regulator Tap Operation in Distribution Networks Due to Electric Vehicle Fast Charging

open access: yesEnergies
Electric vehicles (EVs) are transforming the transportation sector, driven by the rapid expansion of charging infrastructure, including fast-charging stations (FCSs), significantly reducing charging time compared to standard charging stations.
Oscar Mauricio Hernández-Gómez   +3 more
doaj   +1 more source

Voltage to frequency converter Patent [PDF]

open access: yes, 1971
Voltage controlled, variable frequency relaxation oscillator with MOSFET variable current ...
Lokerson, D. C.
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Design of Optimal QFT Controller and Prefilter for Buck Converter Using Metaheuristic Algorithms

open access: yesModelling and Simulation in Engineering, 2018
A buck converter is a step-down switching regulator. Buck convertors are being widely used in industrial applications that rely on regulated output voltage under fluctuating input voltage.
Nitish Katal, Shiv Narayan
doaj   +1 more source

A Human Powered Micro-generator for Charging Electronic Devices [PDF]

open access: yes, 2018
A hand-pulled generator has been designed and tested. A preliminary result has been obtained and discussed. This device was created to provide outlet-free charging. Electronic devices are useful when going out into the wilderness. A portable power supply
Adam, John
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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