Results 81 to 90 of about 136,626 (309)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A review on flicker-free ac-dc LED drivers for single-phase and three-phase ac power grids [PDF]
Light-Emitting Diodes (LEDs) are coming strongly into the lighting market due to their advantages over conventional lighting solutions: energy efficient, controllable in both light and color, long lifetime, lack of a warm-up period and high power density.
Arias Pérez de Azpeitia, Manuel +5 more
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Electric vehicles (EVs) are transforming the transportation sector, driven by the rapid expansion of charging infrastructure, including fast-charging stations (FCSs), significantly reducing charging time compared to standard charging stations.
Oscar Mauricio Hernández-Gómez +3 more
doaj +1 more source
Voltage to frequency converter Patent [PDF]
Voltage controlled, variable frequency relaxation oscillator with MOSFET variable current ...
Lokerson, D. C.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Design of Optimal QFT Controller and Prefilter for Buck Converter Using Metaheuristic Algorithms
A buck converter is a step-down switching regulator. Buck convertors are being widely used in industrial applications that rely on regulated output voltage under fluctuating input voltage.
Nitish Katal, Shiv Narayan
doaj +1 more source
A Human Powered Micro-generator for Charging Electronic Devices [PDF]
A hand-pulled generator has been designed and tested. A preliminary result has been obtained and discussed. This device was created to provide outlet-free charging. Electronic devices are useful when going out into the wilderness. A portable power supply
Adam, John
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source

