Results 191 to 200 of about 4,595,489 (342)

Rodatristat ethyl decreases activity in pulmonary arterial hypertension: results from the ELEVATE-2 trial. [PDF]

Ann Am Thorac Soc
Lachant DJ, Sahay S, Block R, Ossip D, Denning J, Lazarus HM, Parsley E, White RJ.   +7 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Gaps in awareness, treatment, and control of hypertension in Ethiopia: a care cascade analysis using nationally representative data. [PDF]

Prev Med Rep
Brhanie TW.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Change in walking cadence as a digital outcome measure of clinically meaningful improvement in gait speed and 6-minute walk test distance after a mobility intervention in older adults. [PDF]

PLoS One
Rubin DS, Glynn NW, Straczkiewicz M, Danilovich MK, Sciamanna C, Brach JS.   +5 more
europepmc   +1 more source

Statistics Glossary: Design of Experiments & ANOVA

This site, created by authors Valerie Eastor and John H. McColl, lists definitions of key terms related to experimental design and ANOVA. Some of these include factorial, blocking, interaction, experimental design, treatment, variance testing, placebo ...
Eastor, Valerie, McColl, John H.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Rethinking EDSS-based ambulation assessment in multiple sclerosis using continuous variable monitoring. [PDF]

Neurol Res Pract
Werner NM, Schuette M, Hagler R, Voth J, Danajka B, Kirschner P, Heibel M, Ziemssen T, Zettl UK, Meuth SG, Pawlitzki M, Masanneck L.   +11 more
europepmc   +1 more source

Step by step [PDF]

Nature Reviews Cancer, 2006
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source