Results 81 to 90 of about 1,498 (171)

Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter‐compatible endovascular electroencephalogram electrode: A clinical feasibility trial

Epilepsia Open, EarlyView.
Abstract Objective To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP‐01, designed for minimally invasive seizure localization in patients with drug‐resistant epilepsy. Methods This single‐center, prospective, exploratory trial enrolled five patients with drug‐resistant ...
Kota Araki, Yosuke Masuda, Ayataka Fujimoto, Mitsuyo Nishimura, Hisayuki Hosoo, Hiroki Ishida, Takashi Enokizono, Kensuke Kawai, Eiichi Ishikawa, Yuji Matsumaru   +9 more
wiley   +1 more source

Single‐nucleus RNA sequencing reveals ferroptosis as a potential contributor to the pathogenesis of focal cortical dysplasia

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
1. A single‐cell analysis was conducted to investigate the transcriptomic changes in cells within focal cortical dysplasia (FCD). 2. Ferroptosis may play a significant role in the pathogenesis of FCD, potentially contributing to cellular damage and epileptogenesis. 3.
Qingyang Zeng, Fengjun Zhu, Dezhi Cao, Yang Sun, Lin Li, Zeshi Tan, Cong Li, Xiaofan Ren, Yidi Liu, Zhiqiang Lin, Dongfang Zou   +10 more
wiley   +1 more source

IntrAnat Electrodes: A Free Database and Visualization Software for Intracranial Electroencephalographic Data Processed for Case and Group Studies

Frontiers in Neuroinformatics, 2018
In some cases of pharmaco-resistant and focal epilepsies, intracranial recordings performed epidurally (electrocorticography, ECoG) and/or in depth (stereoelectroencephalography, SEEG) can be required to locate the seizure onset zone and the eloquent ...
Pierre Deman, Pierre Deman, Manik Bhattacharjee, Manik Bhattacharjee, François Tadel, François Tadel, Anne-Sophie Job, Anne-Sophie Job, Anne-Sophie Job, Denis Rivière, Denis Rivière, Yann Cointepas, Yann Cointepas, Philippe Kahane, Philippe Kahane, Philippe Kahane, Olivier David, Olivier David   +17 more
doaj   +1 more source

Robotic-Assisted and Image-Guided MRI-Compatible Stereoelectroencephalography [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2017
AbstractBackground: Stereoelectroencephalography has been in regular use at the Montreal Neurological Institute since 1972. The technique has been in constant evolution to incorporate advances in materials, imaging, and robotics technology. MRI-compatible electrodes were introduced in 2007 and robotics in 2011.
Jeffery A. Hall, Hui Ming Khoo
openaire   +2 more sources

Clinical Utility of Z‐Score Distribution Mapping in Epileptogenic Zone Localizations

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Z‐score distribution mapping (Z‐map) is a noninvasive technique for epilepsy surgery planning and provides a comprehensive evaluation of regional variations in the performance of Z‐maps, which is a complementary tool for optimizing stereoelectroencephalography (SEEG) electrode implantation, especially in patients with inconclusive imaging findings or ...
Jinkun Han, Penghu Wei, Sichang Chen, Yanfeng Yang, Yongzhi Shan, Guoguang Zhao   +5 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

SEEG-Based Bilateral Seizure Network Analysis for Neurostimulation Treatment

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Epilepsy patients with drug-resistant seizures emanating from two or more distinct regions of left and right hemispheres are the primary candidates for neurostimulation treatment.
Genchang Peng, Mehrdad Nourani, Jay Harvey   +2 more
doaj   +1 more source

A Hidden Markov Factor Analysis Framework for Seizure Detection in Epilepsy Patients [PDF]

, 2019
Approximately 1% of the world population suffers from epilepsy. Continuous long-term electroencephalographic (EEG) monitoring is the gold-standard for recording epileptic seizures and assisting in the diagnosis and treatment of patients with epilepsy ...
Madadi, Mahboubeh
core   +2 more sources

Resolution of generalized tonic seizures following focal ablative or resective surgery

Epileptic Disorders, Volume 28, Issue 2, Page 333-343, April 2026.
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman, Itay Tokatly Latzer, Aaron E. L. Warren, Jurriaan M. Peters   +3 more
wiley   +1 more source

Electroencephalographic source imaging: a prospective study of 152 operated epileptic patients [PDF]

, 2015
Electroencephalography is mandatory to determine the epilepsy syndrome. However, for the precise localization of the irritative zone in patients with focal epilepsy, costly and sometimes cumbersome imaging techniques are used.
Brodbeck, Verena, Spinelli, Laurent, Lascano, Agustina M., Wissmeier, Michael, Vargas, Maria-Isabel, Vulliemoz, Serge, Pollo, Claudio, Schaller, Karl, Michel, Christoph M., Seeck, Margitta   +9 more
core   +1 more source