Results 171 to 180 of about 53,816 (275)

The Mechanism Underlying the Abnormal Expression of α‐Synuclein in the Cortical Lesions of Patients With FCD Type IIb and TSC

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
The mTOR/GLT‐1 pathway abnormality induces α‐synucleinopathy, contributing to seizures in FCD lesions, which were rescued by treatment with the mTOR inhibitor Rapa or the GLT‐1 enhancer Cef. Intracerebroventricular α‐syn administration attenuated PTZ‐induced seizures in FCD models.
Li Zhang   +6 more
wiley   +1 more source

Prospective Evaluation of Stereotactic Body Radiation Therapy for Reirradiation of Bone Metastases. [PDF]

open access: yesAdv Radiat Oncol
Hammoudeh L   +7 more
europepmc   +1 more source

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

open access: yesEpilepsia, Volume 67, Issue 4, Page 1614-1626, April 2026.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens   +8 more
wiley   +1 more source

Clinical Advantages of Positron Emission Tomography/Computed Tomography and Positron Emission Tomography/Magnetic Resonance in Radiotherapy: A Narrative Review

open access: yesiRADIOLOGY, Volume 4, Issue 2, Page 71-85, April 2026.
Review the clinical application of PET multimodal imaging and compare its clinical advantages. ABSTRACT Positron emission tomography (PET)–based multimodal imaging, including PET/computed tomography (PET/CT) and PET/magnetic resonance (PET/MR), plays an increasingly important role in precision radiotherapy by integrating metabolic and anatomical ...
Yingze Fu   +4 more
wiley   +1 more source

Outcome and Toxicity Profile of Stereotactic Body Radiation Therapy for Adrenal Tumours in Dogs. [PDF]

open access: yesVet Comp Oncol
Thorsen L   +9 more
europepmc   +1 more source

Modeling of Tumor Control Probability in Stereotactic Body Radiation Therapy for Adrenal Tumors

open access: green, 2021
Priscilla K. Stumpf   +5 more
openalex   +2 more sources

Isocitrate Dehydrogenase‐Mutant Astrocytomas: Risk Stratification and Therapeutic Advance

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This graphical abstract synthesizes the core logic of our revised review by linking integrated diagnosis, risk stratification, and trajectory‐based management in IDH‐mutant astrocytomas across CNS WHO Grades 2–4. It highlights lineage‐defining molecular classification (IDH mutation with core co‐alterations), integrated histomolecular grading, and key ...
Shepeng Wei   +3 more
wiley   +1 more source

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