Results 71 to 80 of about 27,712 (197)

The Definitive‐Intent 10‐Fraction Radiotherapy Protocol (‘The Zurich Protocol’) Yields Lasting Tumour Control and Survival in Dogs With Intracranial Meningiomas

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Moderately hypofractionated definitive‐intent radiotherapy protocols can be used for canine intracranial meningiomas to shorten overall treatment time while maintaining tumour control and limiting normal tissue toxicity. This retrospective study evaluated oncologic outcomes, toxicity, and radiation dose‐volume‐related prognostic factors in ...
Carlotta Ahrens   +2 more
wiley   +1 more source

The Confluence of Stereotactic Ablative Radiotherapy and Tumor Immunology

open access: yesClinical and Developmental Immunology, 2011
Stereotactic radiation approaches are gaining more popularity for the treatment of intracranial as well as extracranial tumors in organs such as the liver and lung.
Steven Eric Finkelstein   +6 more
doaj   +1 more source

Use of the IlluminOss Photodynamic Bone Stabilisation System Following Stereotactic Body Radiation Therapy for Limb‐Sparing in Six Dogs With Presumptive Appendicular Osteosarcoma

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma is the most common primary bone tumour in dogs, with approximately 75% of cases occurring in the appendicular skeleton. Standard‐of‐care therapy consists of limb amputation followed by carboplatin chemotherapy. A minority of dogs have limb‐sparing treatments including stereotactic body radiation therapy (SBRT) or surgery. SBRT has
Emily A. Pope   +6 more
wiley   +1 more source

The clinical introduction of MR-guided radiation therapy from a RTT perspective

open access: yesClinical and Translational Radiation Oncology, 2019
The latest development in radiation oncology departments towards high precision and adaptive radiation therapy is the clinical introduction of magnetic resonance image guided radiation therapy (MRgRT).
R. Botman   +5 more
doaj   +1 more source

Cellular mechanisms of radiation‐induced myocyte dysfunction: effects on calcium handling, ion channel regulation and mitochondrial energetics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Dose‐dependent effects of radiation on cardiac electrophysiology and arrhythmia susceptibility. At low radiation doses (left), increased reactive oxygen species (ROS) initiate an ROS–Ca2+ positive feedback loop involving calcium/calmodulin‐dependent protein kinase II (CaMKII) activation, enhanced L‐type Ca2+ current (ICaL ...
Hannah M. Zukowski, Colleen E. Clancy
wiley   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Sacral insufficiency fracture after stereotactic body radiation therapy for sacral metastasis

open access: yesClinical Case Reports, 2018
Key Clinical Message Stereotactic body radiation therapy (SBRT) allows the targeting of high doses of radiation with steep dose gradients. Vertebral fracture is increasingly recognized as an adverse event after SBRT; however, no sacral fractures have ...
Terufumi Kawamoto   +4 more
doaj   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K   +5 more
wiley   +1 more source

An Overview of the Development of Stereotactic Body Radiation Therapy

open access: yesFrontiers in Computing and Intelligent Systems
Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control rate of the tumor and reduce the probability of complications.With the comprehensive development of medical imaging,
Yanqi Zong   +4 more
openaire   +2 more sources

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