Results 81 to 90 of about 27,810 (219)

Non‐Metastatic Squamous Cell Carcinoma of the Oropharynx: Primary Surgery or (Chemo)radiotherapy?

Head &Neck, Volume 48, Issue 9, Page 2541-2556, September 2026.
ABSTRACT Background In patients with locally advanced, non‐metastatic oropharyngeal squamous cell carcinoma (OPSCC), surgery‐based and nonsurgical treatment approaches have not been adequately compared in randomized Phase III clinical trials. Current clinical guidelines recommend various surgical and nonsurgical strategies across disease stages for ...
Primož Strojan, Avraham Eisbruch, June Corry, Sandra Nuyts, Pim de Graaf, Luiz P. Kowalski, Jonathan J. Beitler, Sweet Ping Ng, William M. Mendenhall, M. P. Sreeram, Karthik N. Rao, Anna Luíza Damaceno Araújo, Alfio Ferlito   +12 more
wiley   +1 more source

Integrating Immunotherapy Into Head and Neck Surgery: Bridging Tumor Biology to Perioperative Decision‐Making, a Review

Head &Neck, Volume 48, Issue 9, Page 2570-2583, September 2026.
ABSTRACT Objective To provide a comprehensive review of the biological rationale, clinical evidence, and practical perioperative management of immunotherapy for the head and neck surgeon. Summary Background Data Standard treatment for resectable head and neck squamous cell carcinoma (HNSCC) has reached a survival plateau, with over 50% of patients ...
Nicholas Brian Shannon, Bruce Ashford
wiley   +1 more source

Hypofractionated stereotactic body radiation therapy for elderly patients with stage IIB–IV nonsmall cell lung cancer who are ineligible for or refuse other treatment modalities

Lung Cancer: Targets and Therapy, 2014
Sana D Karam,1 Zachary D Horne,2 Robert L Hong,2 Don McRae,2 David Duhamel,3 Nadim M Nasr2 1Department of Radiation Oncology, University of Colorado, Denver, CO, USA; 2Department of Radiation Oncology, 3Department of Pulmonary/Critical Care Medicine ...
Karam SD, Horne ZD, Hong RL, McRae D, Duhamel D, Nasr NM   +5 more
doaj  

Case Volume and Experience in Stereotactic Radiation: Analysis of a Prospective Peer Review Program

Advances in Radiation Oncology
Purpose: Stereotactic radiation therapy (SRT) is highly effective but carries the risk of significant toxicity. We identified factors associated with SRT plans that require revision in a comprehensive, prospective peer review program conducted across a ...
Luke Peng, MD, Kee-Young Shin, MS, Tara Kosak, MEd, Ayal A. Aizer, MD, John G. Phillips, MD, MPH, Itai M. Pashtan, MD   +5 more
doaj   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Salvage Androgen Deprivation Therapy Use After Definitive Radiotherapy With vs Without Androgen Deprivation Therapy in Prostate Cancer

The Prostate, Volume 86, Issue 13, Page 1341-1351, September 15, 2026.
ABSTRACT Background For patients with unfavorable intermediate or high risk localized prostate cancer receiving definitive radiotherapy, androgen deprivation therapy reduces recurrence and improves survival but is underutilized due to toxicity concerns. Patients who forgo initial ADT may later require salvage ADT.
Jiaye Shen, Aaron J. Katz, Yahui Xie, Ronald C. Chen, Mutlay Sayan   +4 more
wiley   +1 more source

Retrospective Analysis of Survival and Adverse Effects Associated With Stereotactic Body Radiation Therapy in 12 Dogs With Hepatocellular Carcinoma

Veterinary and Comparative Oncology, Volume 24, Issue 3, Page 485-498, September 2026.
ABSTRACT This retrospective analysis evaluated 12 dogs with hepatocellular carcinoma (HCC) who received stereotactic body radiation therapy (SBRT). Dogs received between 6 and 25 Grey (Gy) per fraction for 1–5 fractions for a total dose of 13–30 Gy. Eleven patients (92%) experienced acute adverse effects (AE), with the majority being VRTOG grade 2–3 ...
Victoria Lee Newberry, Mary‐Keara Boss, Del Leary, Tiffany W. Martin   +3 more
wiley   +1 more source

Investigation of Radiation Isocenter Accuracy of Linear Accelerator – New Approach of Comprehensive Evaluation of Gantry, Couch, and Collimator Isocenters

Journal of Medical Physics
Objective: For stereotactic machines, recommendations demand stringent localization and precise delivery, as reflected by isocenter verification. Determining and analyzing the radiation isocenter for all clinical combinations of gantry, collimator, and ...
Avinash Kuppa Rao, Manikandan Palanisamy, G. V. Subrahmanyam, S. P. Swathi, Tamilarasan Mani   +4 more
doaj   +1 more source