Results 121 to 130 of about 226,373 (256)

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Quality requirements for MRI simulation in cranial stereotactic radiotherapy: a guideline from the German Taskforce “Imaging in Stereotactic Radiotherapy” [PDF]

Accurate Magnetic Resonance Imaging (MRI) simulation is fundamental for high-precision stereotactic radiosurgery and fractionated stereotactic radiotherapy, collectively referred to as stereotactic radiotherapy (SRT), to deliver doses of high biological ...
Bäuerle, Tobias, Ruge, Maximilian, Fietkau, Rainer, Ruge, Maximilian I., Grigo, Johanna, Putz, Florian, Wittig, Andrea, Bock, Michael, Karger, Christian P., Hattingen, Elke, Schmitt, Daniela, Bert, Christoph, Schmidt, Manuel A., Blanck, Oliver   +13 more
core   +1 more source

Circumscribed Meningeal Melanocytic Neoplasms: CNS WHO Grade, Molecular Profile, and Clinical Outcomes

Brain Pathology, EarlyView.
In this study including 31 circumscribed meningeal melanocytic neoplasms (melanocytoma, intermediate‐grade melanocytic tumor [IMT], and melanoma), overall survival (OS) differed significantly among the groups, with melanoma showing significantly worse OS than melanocytoma and IMT showing intermediate OS between melanocytoma and melanoma.
Yi Zhu, Nishika Karbhari, Timothy J. Kaufmann, Aditya Raghunathan, Cristiane M. Ida, Cinthya J. Zepeda‐Mendoza, Ian J. Dryden, Shahriar Salamat, Chathu Atherton, Sarah M. Jenkins, Svetomir N. Markovic, Ugur T. Sener, Caterina Giannini   +12 more
wiley   +1 more source

Stereotactic fractionated radiotherapy for multiple brain metastasis treated with single isocenter multitargeted approach: a case report

Journal of Current Oncology and Medical Sciences
Introduction: Adult patients with solid cancers frequently develop brain metastases. Whole brain radiotherapy (WBRT) alone or Stereotactic radiosurgery/radiotherapy (SRS/SRT) alone or in combination can be considered in Brain metastasis.
Siddharth Arora , Kriti Grover
doaj  

Lung Cancer Brain Metastasis: Brain Microenvironmental Adaptation, Therapeutic Resistance and Translational Strategies

Cancer Science, EarlyView.
Lung cancer brain metastasis is shaped by dynamic crosstalk among tumor cells, the blood–brain barrier, glial and immune cells, neurons, and metabolic niches. This review integrates these mechanisms with therapeutic resistance, translational models, CNS delivery, and multidisciplinary treatment strategies.
Jun Yang, Junyi Xiong, Li Ying, Yanyang Zeng, Ziqiang Ouyang, Mei Liu, Meihua Li   +6 more
wiley   +1 more source

Stereotactic radiotherapy in recurrent gynecological cancer: a case series

, 2009
Scarce data are available on the use of extracranial stereotactic radiotherapy in recurrent gynecological tumors. The aim of this report was to analyze the results of our preliminary experience with extracranial stereotactic radiotherapy in locally or ...
Ferrandina, Gabriella, Scambia, Giovanni, Cellini, Numa, Piermattei, Angelo, Cilla, Savino, Morganti, Alessio Giuseppe, Valentini, Vincenzo, Macchia, Gabriella, Grimaldi, Luca, Ferrandina, Maria Gabriella, Salutari, Vanda, Deodato, Francesco, Lorusso, Domenica   +12 more
core   +1 more source

Advances in Radiotherapy for Neoadjuvant Therapy of Stage III Non‐Small Cell Lung Cancer

Cancer Science, EarlyView.
This review summarizes three neoadjuvant radiotherapy techniques for stage III NSCLC, highlighting SFRT's low‐toxicity dual immune‐tumor control benefits and radioimmunotherapy's superior pathological response to guide precise multimodal treatment. ABSTRACT This review aims to systematically summarize the mechanisms of action, clinical evolution, and ...
Qinrong Mao, Yuanchun Yu, Yan Fang, Shaofeng Zhu, Chengjin Tang, Jing Cai   +5 more
wiley   +1 more source

[Hypofractionated stereotactic radiotherapy of bone metastases]

, 2014
Hypofractionated stereotactic radiotherapy can deliver high doses of bone metastases while sparing adjacent healthy tissue not only for a decompressive or analgesic purpose, but also to improve the local control of the irradiated region. Various phases I
Pichon, B., Bourgier, Céline, Mahe, M. A., Supiot, S., Thillays, F.   +4 more
core   +1 more source

Biopsy of Iris and Anterior Chamber Tumours: Fine Needle, Minimally Invasive and Excision Techniques ‐ Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Several benign, inflammatory and malignant lesions can present as iris or anterior chamber masses, including iris naevi, cysts, adenomas, leiomyomas, nodules, vascular tumours, melanomas, metastases, as well as iris and pigment epithelium adenocarcinomas. Fortunately, benign iris lesions are much more common than malignant tumours and many can
Charles N. J. McGhee, Joevy Z. Lim, Peter W. Hadden, Jie Zhang   +3 more
wiley   +1 more source

Stereotactic Body Radiaton Therapy for 15 Patients with Small Lung Neoplasms

Chinese Journal of Lung Cancer, 2011
Background and objective It has been known that stereotactic radiotherapy has been widely used in clinical practice. The aim of this study is to evaluate the feasibility to treat small lung neoplasms with hypofraction stereotactic radiotherapy.
Rong YU, Yongheng LI, Guangying ZHU
doaj