Results 51 to 60 of about 9,592,818 (278)

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Clinical study on deep brain electrode implantation assisted by ROSA system

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2015
Objective To evaluate the accuracy and safety of deep brain electrode implantation assisted by robotized stereotactic assistant (ROSA) system. Methods A total of 6 epileptic patients who had difficulty in positioning of epileptogenic focus underwent ...
Zhi-qi MAO   +6 more
doaj  

Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection

open access: yesJournal of Visualized Experiments, 2016
Replication defective lentiviruses or retroviruses are capable of stably integrating transgenes into the genome of an infected host cell. This technique has been widely used to encode fluorescent proteins, opto- or chemo-genetic controllers of cell ...
Catherine J. Fricano-Kugler   +4 more
semanticscholar   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Noradrenergic Neuromodulation of Septal Circuitry Mediating Hoarding Behaviour in Male Wistar Rats [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2021
Background: Ingestive appetitive behaviour has been less delved into in research. Considering the connection of food hoarding with energy balance, unperplexing its exact neurophysiological mechanism will help in combating obesity.
Krishnakant B. Patil , Ashwini N. Patil
doaj  

The Subcortical Atlas of the Rhesus Macaque (SARM) for neuroimaging

open access: yesNeuroImage, 2021
Digitized neuroanatomical atlases that can be overlaid onto functional data are crucial for localizing brain structures and analyzing functional networks identified by neuroimaging techniques.
Renée Hartig   +7 more
doaj   +1 more source

Electrophysiological Measurement of Rat Atrial Epicardium Using a Novel Stereotaxic Apparatus.

open access: yesInternational Heart Journal, 2019
Flexible, in vivo maneuverable electrophysiology mapping techniques are not available in rat models. A novel cardiac stereotactic electrophysiology epicardial mapping system (CREAMS) allows for various measurements, including: (1) recording unipolar ...
Boyuan Fan   +8 more
semanticscholar   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

The history of stereotactic technology

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2015
This paper takes an overall review on the development of stereotactic technology. During the year 1947-2015, the history of stereotactic technology can be divided into five stages: 1) frame-based and stereotactic technology (1947-1972); 2) frame-based
Ye-han WANG
doaj  

Compact Laser Doppler Flowmeter (LDF) Fundus Camera for the Assessment of Retinal Blood Perfusion in Small Animals. [PDF]

open access: yesPLoS ONE, 2015
Noninvasive techniques for ocular blood perfusion assessment are of crucial importance for exploring microvascular alterations related to systemic and ocular diseases.
Marielle Mentek   +7 more
doaj   +1 more source

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