Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M. +3 more
core +2 more sources
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Noradrenergic Neuromodulation of Septal Circuitry Mediating Hoarding Behaviour in Male Wistar Rats [PDF]
Background: Ingestive appetitive behaviour has been less delved into in research. Considering the connection of food hoarding with energy balance, unperplexing its exact neurophysiological mechanism will help in combating obesity.
Krishnakant B. Patil , Ashwini N. Patil
doaj
The Subcortical Atlas of the Rhesus Macaque (SARM) for neuroimaging
Digitized neuroanatomical atlases that can be overlaid onto functional data are crucial for localizing brain structures and analyzing functional networks identified by neuroimaging techniques.
Renée Hartig +7 more
doaj +1 more source
Placenta ingestion by rats enhances d- and k-opioid antinociception, but suppresses m-opioid antinociception [PDF]
Ingestion of placenta or amniotic fluid produces a dramatic enhancement of centrally mediated opioid antinociception in the rat. The present experiments investigated the role of each opioid receptor type (m, d, k) in the antinociception-modulating ...
DiPirro, Jean M., Kristal, Dr. Mark B.
core
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
The history of stereotactic technology
This paper takes an overall review on the development of stereotactic technology. During the year 1947-2015, the history of stereotactic technology can be divided into five stages: 1) frame-based and stereotactic technology (1947-1972); 2) frame-based
Ye-han WANG
doaj
Objective To investigate the feasibility and efficacy of deep brain stimulation (DBS) in the treatment of Parkinson's disease (PD) after pallidum or thalamus lesion, and to analyze its therapeutic strategy.
Jia⁃ming MEI +4 more
doaj
Compact Laser Doppler Flowmeter (LDF) Fundus Camera for the Assessment of Retinal Blood Perfusion in Small Animals. [PDF]
Noninvasive techniques for ocular blood perfusion assessment are of crucial importance for exploring microvascular alterations related to systemic and ocular diseases.
Marielle Mentek +7 more
doaj +1 more source
Encoding of temporal probabilities in the human brain [PDF]
Anticipating the timing of future events is a necessary precursor to preparing actions and allocating resources to sensory processing. This requires elapsed time to be represented in the brain and used to predict the temporal probability of upcoming ...
Bahrami, B. +3 more
core +1 more source

