Results 41 to 50 of about 2,053 (128)

Using stereo‐electroencephalography data to model the optimal intracranial venous sinus location for an endovascular seizure detection device: A feasibility study

Epilepsia Open, Volume 10, Issue 6, Page 1938-1952, December 2025.
Abstract Objective We investigated the theoretical optimal venous location for an endovascular seizure detection device using stereo‐EEG (SEEG) data. Methods Six venous sinus segments from consecutive SEEG patients: anterior, middle, and posterior sagittal sinus (SS‐A, SS‐M, SS‐P), straight sinus, and the ipsilateral/contralateral (relative to primary ...
Thanomporn Wittayacharoenpong, Gil Rind, Martin Hunn, Matthew Gutman, Matt Hudson, Zhibin Chen, Joshua Laing, Terence J. O'Brien, Nicholas Opie, Andrew Neal   +9 more
wiley   +1 more source

MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures

Journal of Magnetic Resonance Imaging, Volume 62, Issue 5, Page 1280-1295, November 2025.
ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez, Thomas Lilieholm, Walter F. Block   +2 more
wiley   +1 more source

Automated Marker Localization in the Planning Phase of Robotic Neurosurgery

IEEE Access, 2017
Accurate patient registration is a critical issue in medical image-guided interventions. The neurosurgical robotic system RObotic Neuro-NAvigation (RONNA) uses four retro-reflective spheres, on a marker attached to the patient's cranial bone, for patient
Filip Suligoj, Marko Svaco, Bojan Jerbic, Bojan Sekoranja, Josip Vidakovic   +4 more
doaj   +1 more source

Different strategies in the management of thalamic space-occupying lesions

Egyptian Journal of Neurosurgery, 2020
Introduction Thalamic space-occupying lesions (SOL) are considered challenging for microsurgical removal. Unfortunately, the pathological features of lesions occurring in the thalamic region are different with a wide variation in clinical behavior and ...
Ahmed Abdel Aziz Fayed, Osama Abdel Aziz, Mohamed Eshra   +2 more
doaj   +1 more source

Precise Electrode Co‐Alignment in Deep Brain Stimulation Fusing Neuroimaging and Electrophysiology

European Journal of Neuroscience, Volume 62, Issue 10, November 2025.
ABSTRACT We present a multimodal framework to improve the precision of electrode placement in deep brain stimulation (DBS) by fusing preoperative neuroimaging with intraoperative electrophysiology for accurate electrode co‐alignment. The workflow integrates automated subthalamic nucleus (STN) segmentation from preoperative MRI using a two‐step ...
Igor Varga, Daniel Novak, Dusan Urgosik, Jan Kybic, Filip Ruzicka, Pavel Filip, Robert Jech, Andreas Horn, Eduard Bakstein   +8 more
wiley   +1 more source

Robot Assisted MRI-Guided LITT of the Anterior, Lateral, and Medial Temporal Lobe for Temporal Lobe Epilepsy

Frontiers in Neurology, 2020
Robotic systems have fundamentally altered the landscape of functional neurosurgery. These allow automated stereotaxy with high accuracy and reliability, and are rapidly becoming a mainstay in stereotactic surgeries such as deep brain stimulation (DBS ...
Kunal Gupta, Kunal Gupta, Adam S. Dickey, Ranliang Hu, Edward Faught, Jon T. Willie, Jon T. Willie   +6 more
doaj   +1 more source

The Next Frontier in Parkinson's Disease Treatment: A Narrative Review of Innovative Neurosurgical and Gene Therapy Approaches

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Parkinson's disease (PD) is a progressive neurological condition that consists of both motor and non‐motor symptoms that considerably deteriorate the quality of life. Pharmacological treatments, primarily levodopa, have been used to manage PD. However, side effects such as dyskinesias and motor fluctuations frequently limit
Muhammad Shaheer Bin Faheem, Muhammad Haroon‐Ul‐Rasheed, Rohma Aftab, Qasra Faheem, Faheem Feroze, Hafiza Qurat Ul Ain, Sumaya Samadi   +6 more
wiley   +1 more source

Paired Deep Brain Stimuli Elicit Short‐Term Facilitation in Globus Pallidus Interna and Subthalamic Nucleus

Movement Disorders, Volume 40, Issue 8, Page 1636-1647, August 2025.
Abstract Background Deep brain stimulation (DBS) elicits oscillatory local field potentials in patients with Parkinson's disease (PD) and other movement disorders. Greater knowledge about the fast dynamics of these neural responses could shed light on circuit pathophysiology and inform novel approaches to neuromodulation therapies.
Sarah Brinkerhoff, Arie Nakhmani, Alex Varghese, Cameron Gordon, Christopher L. Gonzalez, J. Nicole Bentley, Marshall T. Holland, Harrison C. Walker   +7 more
wiley   +1 more source

Stereotactic biopsies of brain lesions Biópsia estereotáxica de lesões encefálicas

Arquivos de Neuro-Psiquiatria, 2009
OBJECTIVE: In the majority of cases, the correct treatment of brain lesions is possible only when the histopathological diagnosis is made. Several deep-seated lesions near eloquent areas are not safely approached by the classical neurosurgical procedures.
Manoel Jacobsen Teixeira, Erich Talamoni Fonoff, Mauricio Mandel, Hélvio Leite Alves, Sérgio Rosemberg   +4 more
doaj   +1 more source

Psychosocial distress and persistent adverse events in long‐term survivors of stage IV melanoma – a cross‐sectional questionnaire study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 7, Page 832-842, July 2025.
Summary Background Immune checkpoint inhibitors and targeted therapies have improved survival in patients with stage IV melanoma. However, the challenges faced by long‐term survivors remain unclear. The long‐term toxicity and psychosocial impact of these treatments in real‐world patients have yet to be reported.
Markus Reitmajer, Norbert Schäffeler, Anne Bach, Lena Nanz, Teresa Amaral, Ulrike Leiter, Lukas Flatz, Andrea Forschner   +7 more
wiley   +1 more source